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SUDEP discussions with patients and families

Practical Neurology, 2012
SUDEP is clearly a very important issue. Patients and their representatives (and in Scotland our legal system) would like consistency and clarity in how this information is conveyed. It behooves us to find a way to pass on our concerns in a way that acknowledges the needs, fears and circumstances of each individual patient and, where appropriate,of ...
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Ictal asystole and SUDEP

Neurology, 2007
The most frightening consequence of uncontrolled epilepsy is sudden unexplained death (SUDEP). Population studies suggest a risk in the range of 1 to 5 per 1,000 patient-years,1,2 and in high risk populations with neurologic impairments this rate is even higher. How seizures cause sudden death is still debated.
Norman K. So, Michael R. Sperling
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SUDEP in inherited metabolic epilepsies

Epilepsy & Behavior
Inherited metabolic epilepsies (IMEs) have an increased susceptibility for early mortality, including sudden unexpected death in epilepsy (SUDEP), as they often manifest with frequent drug-resistant seizures, including bilateral tonic-clonic and nocturnal seizures.
Itay Tokatly Latzer   +4 more
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The incidence of SUDEP

Neurology, 2017
To identify all cases of sudden unexpected death in epilepsy (SUDEP) among people in Sweden during 1 year and to determine the SUDEP incidence in relation to age, sex, and psychiatric comorbidity.We included all individuals with a hospital-based ambulatory care or hospital discharge diagnosis of epilepsy in the Swedish National Patient Registry during ...
Olafur, Sveinsson   +3 more
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SUDEP

Neurology, 2017
Sudden unexpected death in epilepsy (SUDEP) was originally defined as a sudden, unexpected death in an individual with epilepsy, witnessed or not, and not associated with drowning or status epilepticus, for which a cause cannot be identified upon autopsy examination.1 Cases can be divided into definite, probable, and possible based upon the level of ...
Jeffrey, Buchhalter, Gregory D, Cascino
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Retrospective comparison of interictal cardiac biomarkers of SUDEP or near-SUDEP with PNES patients

Epilepsy & Behavior
Interictal QTc-interval changes and heart rate variability (HRV) are reported in people succumbing to sudden unexpected death in epilepsy (SUDEP). We evaluated cardiac biomarkers recorded during video-EEG monitoring in nine SUDEP/near-SUDEP cases and compared them to 9 age- and gender-matched people with psychogenic nonepileptic episodes (PNES) treated
Alejandra Duque Ramirez   +3 more
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Cardiac and Autonomic Mechanisms Contributing to SUDEP

Journal of Clinical Neurophysiology, 2015
Sudden unexpected death in epilepsy is likely caused by a cascade of events affecting the vegetative nervous system leading to cardiorespiratory failure and death. Multiple genetic, electrophysiological, neurochemical, and pharmacological cardiac alterations have been associated with epilepsy, which can affect autonomic regulation of the heart and ...
Adriana C, Bermeo-Ovalle   +2 more
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SUDEP and Cardiac Arrhythmia

2013
A 19-year-old male had drug-resistant epilepsy and recurrent focal and generalized seizures. Trauma was reported in early childhood after he was struck by an automobile at the age of 5. This resulted in significant traumatic brain injury and cognitive impairment.
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Seizures and Sudden Death Beyond SUDEP

Neurology
Many physicians and researchers are familiar with the tragic phenomenon known as sudden infant death syndrome (SIDS), the leading cause of postneonatal mortality in high-resource countries. A less familiar category of unexplained deaths is the problem of sudden unexplained death in childhood (SUDC), a more rare and unusual presentation of sudden death ...
Richard D. Goldstein, Annapurna Poduri
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Is there a seasonal influence on SUDEP?

Epilepsy & Behavior, 2021
Fulvio A. Scorza   +4 more
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