Results 201 to 210 of about 5,831 (244)
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SUDEP: Living with the knowledge
Epilepsy Research, 2023To understand how knowledge of sudden unexpected death in epilepsy (SUDEP) impacted the lives of adult persons with epilepsy (PWE) and primary caregivers of both adults and children with epilepsy.The principles of fundamental qualitative description guided this descriptive and exploratory qualitative study to document patients' and caregivers ...
Robyn Whitney +5 more
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Improving prediction of sudden unexpected death in epilepsy: From SUDEP‐7 to SUDEP‐3
Epilepsia, 2021AbstractObjectiveSudden unexpected death in epilepsy (SUDEP) is a significant cause of mortality in epilepsy. The aim of this study is to evaluate the validity of the SUDEP‐7 inventory and its components as tools for predicting SUDEP risk, and to develop and validate an improved inventory.MethodsThe study included 28 patients who underwent video ...
Roozbeh Tarighati Rasekhi +6 more
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Type, Etiology, and Duration of Epilepsy as Risk Factors for SUDEP
Neurology, 2023Background and Objectives We conducted a nationwide case-control study in Sweden to investigate the risk of sudden unexpected death in epilepsy (SUDEP) in relation to epilepsy duration, epilepsy type, and etiology in combination with occurrence and ...
Ó. Sveinsson +3 more
semanticscholar +1 more source
Epilepsy & Behavior, 2022
Risk of sudden unexpected death in epilepsy (SUDEP) in children is influenced by different factors such as etiology, seizure type and frequency, treatment, and environment. A greater severity of epilepsy, in terms of seizure frequency, seizures type, especially with nocturnal generalized tonic-clonic seizures (GTCS), and resistance to anti-seizure ...
Marina Trivisano +5 more
openaire +2 more sources
Risk of sudden unexpected death in epilepsy (SUDEP) in children is influenced by different factors such as etiology, seizure type and frequency, treatment, and environment. A greater severity of epilepsy, in terms of seizure frequency, seizures type, especially with nocturnal generalized tonic-clonic seizures (GTCS), and resistance to anti-seizure ...
Marina Trivisano +5 more
openaire +2 more sources
Are we there yet ? : A critical evaluation of SUDEP models.
Epilepsia, 2023Although animal models have helped to elaborate meaningful hypotheses about the pathophysiology of Sudden Unexpected Death in Epilepsy (SUDEP), specific prevention strategies are still lacking, potentially reflecting the limitations of these models and ...
Jonathon Smith +6 more
semanticscholar +1 more source
Science Translational Medicine, 2020
Antisense oligonucleotide administration reduces seizures and SUDEP incidence in a mouse model of Dravet syndrome. A solution for Dravet? Mutations in SCN1A, the gene encoding for the sodium channel NaV1.1, cause Dravet syndrome (DS), a developmental ...
Zhou Han +11 more
semanticscholar +1 more source
Antisense oligonucleotide administration reduces seizures and SUDEP incidence in a mouse model of Dravet syndrome. A solution for Dravet? Mutations in SCN1A, the gene encoding for the sodium channel NaV1.1, cause Dravet syndrome (DS), a developmental ...
Zhou Han +11 more
semanticscholar +1 more source
The role of convulsive seizures in SUDEP
Autonomic Neuroscience, 2021Convulsive seizures are the most consistently reported risk factor for SUDEP. However, the precise mechanisms by which convulsive seizures trigger fatal cardiopulmonary changes are still unclear. Additionally, it is not clear why some seizures cause death when most do not.
Allyson A. Pickard, Maromi Nei
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Resolving ambiguities in SUDEP classification [PDF]
Epilepsia, 2018 SummaryObjectiveTo examine the consistency of applying the Nashef et al (2012) criteria to classify sudden unexpected death in epilepsy (SUDEP).MethodsWe reviewed cases from the North American SUDEP Registry (n = 250) and Medical Examiner Offices (n = 1301: 698 Maryland, 457 New York City, 146 San Diego). Two epileptologists with expertise in SUDEP and
Orrin Devinsky +7 more
openaire +2 more sources
Neurology, 2015
In 1904, Spratling noted that single, brief seizures kill 3%–4% of people with epilepsy.1 More recently, knowledge about sudden unexpected death in epilepsy (SUDEP) has grown dramatically. Our conceptualization of SUDEP has crystalized. We have evidence that SUDEPs largely follow seizures2 and our collective knowledge suggests that preventing seizures,
Lina Nashef, Orrin Devinsky
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In 1904, Spratling noted that single, brief seizures kill 3%–4% of people with epilepsy.1 More recently, knowledge about sudden unexpected death in epilepsy (SUDEP) has grown dramatically. Our conceptualization of SUDEP has crystalized. We have evidence that SUDEPs largely follow seizures2 and our collective knowledge suggests that preventing seizures,
Lina Nashef, Orrin Devinsky
openaire +3 more sources
Epilepsy & Behavior, 2020
The potential for an epileptic seizure to end life has been known throughout history, although the cause of many such deaths is still not understood. Over the last 25 years there has been increasing interest in the phenomenon of Sudden Unexpected Death in Epilepsy (SUDEP) leading to an upswing in the investigation of epilepsy-related mortality ...
openaire +3 more sources
The potential for an epileptic seizure to end life has been known throughout history, although the cause of many such deaths is still not understood. Over the last 25 years there has been increasing interest in the phenomenon of Sudden Unexpected Death in Epilepsy (SUDEP) leading to an upswing in the investigation of epilepsy-related mortality ...
openaire +3 more sources