Results 81 to 90 of about 4,113 (218)
Abstract Lennox–Gastaut syndrome (LGS) is one of the most severe, yet one of the most discussed, childhood‐onset developmental and epileptic encephalopathies (DEEs). Dissent among epileptologists on the definition and minimum set of electroclinical features derives from the high etiological heterogeneity within the syndrome, which could make its ...
Antonella Riva +40 more
wiley +1 more source
Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis
Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi +10 more
wiley +1 more source
Abstract Objectives This study explored the safety and effectiveness of adjunctive cenobamate (CNB) in patients with different levels of drug‐resistant epilepsy (DRE) in a real‐world setting, including its impact on the use of co‐antiseizure medication (co‐ASM). Methods This was a single‐center, retrospective, observational study.
Juan María Sánchez‐Caro +3 more
wiley +1 more source
Balancing Safety and Independence for People With Epilepsy Under Threat of SUDEP [PDF]
Katherine H. Noe
openalex +1 more source
Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome [PDF]
J. Helen Cross +12 more
openalex +1 more source
Spreading depolarization and its influence on epileptiform activity
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque +2 more
wiley +1 more source
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson +11 more
wiley +1 more source
Heart diseases play a vital role in sudden unexpected death in epilepsy
Sudden unexpected death in epilepsy (SUDEP) indicates sudden death without a definite cause in epileptics, especially during seizures or interictal phase.
Ze-ning SHI, Xiao-jun SU, Li-ping ZOU
doaj
Non-EEG seizure-detection systems and potential SUDEP prevention: State of the art [PDF]
Anouk Van de Vel +8 more
openalex +1 more source
Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus +11 more
wiley +1 more source

