Results 121 to 130 of about 469,337 (306)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Self-Sufficiency in Richland County, Illinois [PDF]
, 2009 The struggles facing many Illinois families today did not begin with the current economic crisis. Economic security has been steadily eroding throughout the last few decades.
core
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1964 Summary The concept of sufficiency can be examined locally for a neighbourhood of a parameter point θ0 and it leads to an estimate that has minimum variance among locally-unbiased estimates (Fraser, 1964). This local estimate generates the natural global estimate for the case of the simple exponential model, but it does not do so for the
openaire +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Energy sufficiency for deep decarbonization: A modeling framework
Nexus: This work explores the concept and modeling of energy sufficiency, differentiating it from energy efficiency. Both elements are vital to rethinking established systems of production and consumption in the face of energy crises and climate change.
Jingjing Zhang +5 more
doaj +1 more source
Self-Sufficiency in Lee County, Illinois [PDF]
, 2009 The struggles facing many Illinois families today did not begin with the current economic crisis. Economic security has been steadily eroding throughout the last few decades.
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Self-Sufficiency in Lawrence County, Illinois [PDF]
, 2009 The struggles facing many Illinois families today did not begin with the current economic crisis. Economic security has been steadily eroding throughout the last few decades.
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Self-Sufficiency in Jefferson County, Illinois [PDF]
, 2009 The struggles facing many Illinois families today did not begin with the current economic crisis. Economic security has been steadily eroding throughout the last few decades.
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