Results 131 to 140 of about 469,337 (306)

Transformations and Sufficiency

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1965
Summary Barnard (1963) gave a definition of the sufficiency of T  2 for θ  2 in the absence of knowledge of θ  1 using groups of transformations. A possible generalization of this is implicit in the method of obtaining fiducial distributions by sets of transformations described by Sprott (1963).
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Self-Sufficiency in Bureau County, Illinois [PDF]

open access: yes, 2009
The struggles facing many Illinois families today did not begin with the current economic crisis. Economic security has been steadily eroding throughout the last few decades.

core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Self-Sufficiency in Kankakee County, Illinois [PDF]

open access: yes, 2009
The struggles facing many Illinois families today did not begin with the current economic crisis. Economic security has been steadily eroding throughout the last few decades.

core  

Sufficient data [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2016
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Self-Sufficiency in LaSalle County, Illinois [PDF]

open access: yes, 2009
The struggles facing many Illinois families today did not begin with the current economic crisis. Economic security has been steadily eroding throughout the last few decades.

core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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