Results 61 to 70 of about 244,425 (248)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A New Conjugate Gradient for Unconstrained Optimization Based on Step Size of Barzilai and Borwein
Science Journal of University of Zakho, 2016 In this paper, a new formula of is suggested for conjugate gradient method of solving unconstrained optimization problems based on step size of Barzilai and Borwein.
Salah G. Shareef, Alaa L. Ibrahim
doaj
A Novel Conjugate Gradient Algorithm as a Convex Combination of Classical Conjugate Gradient Methods
Kurdistan Journal of Applied ResearchConjugate gradient (CG) algorithms are constructive for handling large-scale nonlinear optimization problems. One optimization technique intended to address unconstrained optimization issues effectively is the hybrid conjugate gradient (HCG) algorithm ...
Sara Sahib Mohammed Zaki +2 more
doaj +1 more source
A new accelerated conjugate gradient method for large-scale unconstrained optimization
Journal of Inequalities and Applications, 2019 In this paper, we present a new conjugate gradient method using an acceleration scheme for solving large-scale unconstrained optimization. The generated search direction satisfies both the sufficient descent condition and the Dai–Liao conjugacy condition
Yuting Chen, Mingyuan Cao, Yueting Yang
doaj +1 more source
New Scale Dai-Yaun Conjugate Gradient Method for Unconstrained Optimization [PDF]
Al-Rafidain Journal of Computer Sciences and Mathematics, 2013 Conjugate gradient algorithm is widely used for solving large-scale unconstrained optimization problems, because they do not need the storage of matrices.
Hamsa Chilmerane
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
New Conjugate Gradient Method for Unconstrained Optimization with Logistic Mapping
Science Journal of University of Zakho, 2016 In this paper , we suggested a new conjugate gradient algorithm for unconstrained optimization based on logistic mapping, descent condition and sufficient descent condition for our method are provided. Numerical results show that our presented algorithm
Shareef G. Shareef +2 more
doaj
Efficient hybrid conjugate gradient techniques for vector optimization
Results in Control and OptimizationScalarization approaches transform vector optimization problems (VOPs) into single-objective optimization but have trade-offs: information loss, subjective weight assignments, and limited representation of the Pareto front.
Jamilu Yahaya, Poom Kumam
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source