Results 101 to 110 of about 845,542 (252)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

A dimension reduction assisted credit scoring method for big data with categorical features

Financial Innovation
In the past decade, financial institutions have invested significant efforts in the development of accurate analytical credit scoring models. The evidence suggests that even small improvements in the accuracy of existing credit-scoring models may ...
Tatjana Miljkovic, Pei Wang
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Discussion on ‘Review of sparse sufficient dimension reduction’

Statistical Theory and Related Fields, 2020
Xin Chen
doaj   +2 more sources

Finite-time stability for fractional-order fuzzy neural network with mixed delays and inertial terms

AIMS Mathematics
This paper explored the finite-time stability (FTS) of fractional-order fuzzy inertial neural network with mixed delays. First, the dimension of the model was reduced by the order reduction method.
Tiecheng Zhang , Liyan Wang , Yuan Zhang, Jiangtao Deng   +3 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The Consequences of Dimension Reduction for Open Graded Friction Course (OGFC) Asphalt Mixtures: Morphological Characteristics and Finite Element Model (FEM) Simulation

Buildings
Asphalt mixtures exhibit complex mechanical behaviors due to their multiphase internal structures. To provide better characterizations of asphalt pavements under various forms of potential distress, a two-dimensional (2D) finite element simulation based ...
Kai Li, Quan Liu, Yuan Tian, Cong Du, Zhixiang Xu   +4 more
doaj   +1 more source

Graph informed sufficient dimension reduction

, 2020
We develop in this manuscript a new method for performing dimension reduction when probabilistic graphical models are being used to perform estimation of parameters. The procedure enriches the domain of application of dimension reduction techniques to settings where (i) p the number of variables in the model is much larger than the available sample ...
Pircalabelu, Eugen, Andreas Artemiou
openaire   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source