Results 81 to 90 of about 5,211,856 (273)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Sufficient dimension reduction for complex data structures [PDF]
, 2014 University of Minnesota Ph.D. dissertation. June 2014. Major: Statistics. Advisor: Ralph Dennis Cook. 1 computer file (PDF); xi, 132 pages.Data with complex structures, such as array-valued predictors, or responses, are commonly encountered in modern ...
Ding, Shanshan
core
RMFGP: A Rotated Multi-Fidelity Gaussian Process Framework for Supervised Dimension Reduction
MathematicsHigh-dimensional surrogate modeling with limited high-fidelity data poses a major challenge in uncertainty quantification. Classical supervised dimension reduction methods often fail in this setting due to insufficient accurate observations, while low ...
Jiahao Zhang, Shiqi Zhang, Guang Lin
doaj +1 more source
IEEE Access, 2019 This paper proposes an improved protein feature expression called segmented amino acid composition in position-specific scoring matrix (PSSM-SAA) in the field of subcellular localization prediction.
Shunfang Wang +5 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Condition Assessment of PCI Bridge Girder a Result of The Reduction Prestressing Force
EPJ Web of Conferences, 2014 PCI bridge girders is known and widely used for many construction e.g.: bridge, wharf, flyover, and other application. PC Bridge girders have two types: Pre - tensioned girders and post - tensioned girders.
Suangga Made +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Group-wise sufficient dimension reduction with principal fitted components
, 2016 Sufficient dimension reduction methodologies in regressions of Y on a p-variate X aim at obtaining a reduction R(X) ∈ Rᵈ, d ≤ p, that retains all the regression information of Y in X.
Adragni, K. +4 more
core +1 more source
Multivariate response directional regression: a projective resampling approach
Journal of Big DataIn high dimensional data analysis, directional regression is a widely used method for implementing linear sufficient dimension reduction by extracting core information from the complex data structure.
Ahreum Lee, Kyongwon Kim
doaj +1 more source