Results 111 to 120 of about 846,250 (270)
A dimension reduction assisted credit scoring method for big data with categorical features
Financial InnovationIn the past decade, financial institutions have invested significant efforts in the development of accurate analytical credit scoring models. The evidence suggests that even small improvements in the accuracy of existing credit-scoring models may ...
Tatjana Miljkovic, Pei Wang
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Discussion on ‘Review of sparse sufficient dimension reduction’
Statistical Theory and Related Fields, 2020 Xin Chen
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BuildingsAsphalt mixtures exhibit complex mechanical behaviors due to their multiphase internal structures. To provide better characterizations of asphalt pavements under various forms of potential distress, a two-dimensional (2D) finite element simulation based ...
Kai Li +4 more
doaj +1 more source
DIMENSION REDUCTION TRANSFORMATIONS IN DISCRIMINANT ANALYSIS [PDF]
Dimension reduction transformations in discriminant analysis are introduced. Their properties, as well as sufficient conditions for their characterization, are studied.
Adolfo Hernández, Santiago Velilla
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
An Adaptive Domain Partitioning Technique for Meshfree-Type Methods
Journal of Applied Mathematics, 2012 An overlapping domain partitioning based on adapting nodes is presented for the meshless-type methods. The decomposition of the domain is carried out based on the distribution of the nodes produced rather than the geometry of the problem.
Kamal Shanazari
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Graph informed sufficient dimension reduction
, 2020 We develop in this manuscript a new method for performing dimension reduction when probabilistic graphical models are being used to perform estimation of parameters. The procedure enriches the domain of application of dimension reduction techniques to settings where (i) p the number of variables in the model is much larger than the available sample ...
Pircalabelu, Eugen, Andreas Artemiou
openaire +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source