Results 111 to 120 of about 845,542 (252)

An Adaptive Domain Partitioning Technique for Meshfree-Type Methods

open access: yesJournal of Applied Mathematics, 2012
An overlapping domain partitioning based on adapting nodes is presented for the meshless-type methods. The decomposition of the domain is carried out based on the distribution of the nodes produced rather than the geometry of the problem.
Kamal Shanazari
doaj   +1 more source

DIMENSION REDUCTION TRANSFORMATIONS IN DISCRIMINANT ANALYSIS [PDF]

open access: yes
Dimension reduction transformations in discriminant analysis are introduced. Their properties, as well as sufficient conditions for their characterization, are studied.
Adolfo Hernández, Santiago Velilla
core  

Sufficient dimension reduction for feature matrices

open access: yes, 2023
We address the problem of sufficient dimension reduction for feature matrices, which arises often in sensor network localization, brain neuroimaging, and electroencephalography analysis. In general, feature matrices have both row- and column-wise interpretations and contain structural information that can be lost with naive vectorization approaches. To
openaire   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Pseudo likelihood and dimension reduction for data with nonignorable nonresponse

open access: yesStatistical Theory and Related Fields, 2018
Tang et al. (2003. Analysis of multivariate missing data with nonignorable nonresponse. Biometrika, 90(4), 747–764) and Zhao & Shao (2015. Semiparametric pseudo-likelihoods in generalized linear models with nonignorable missing data.
Ji Chen, Bingying Xie, Jun Shao
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Markov Boundary Discovery with Ridge Regularized Linear Models

open access: yesJournal of Causal Inference, 2016
Ridge regularized linear models (RRLMs), such as ridge regression and the SVM, are a popular group of methods that are used in conjunction with coefficient hypothesis testing to discover explanatory variables with a significant multivariate association ...
Strobl Eric V., Visweswaran Shyam
doaj   +1 more source

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