Results 41 to 50 of about 103,963 (248)
Multiple phenotype association tests based on sliced inverse regression
Background Joint analysis of multiple phenotypes in studies of biological systems such as Genome-Wide Association Studies is critical to revealing the functional interactions between various traits and genetic variants, but growth of data in ...
Wenyuan Sun +3 more
doaj +1 more source
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier +10 more
wiley +1 more source
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen +21 more
wiley +1 more source
Conditional variance estimator for sufficient dimension reduction
23 pages, 3 ...
Fertl, Lukas, Bura, Efstathia
openaire +2 more sources
ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley +1 more source
ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig +7 more
wiley +1 more source
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Model averaging‐based sufficient dimension reduction
Sufficient dimension reduction is intended to project high‐dimensional predictors onto a low‐dimensional space without loss of information on the responses. Classical methods, such as sliced inverse regression, sliced average variance estimation and directional regression, are backbones of many modern sufficient dimension methods and have gained ...
Min Cai, Ruige Zhuang, Zhou Yu, Ping Wu
openaire +2 more sources
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Accelerating of Image Retrieval in CBIR System with Relevance Feedback
Content-based image retrieval (CBIR) system with relevance feedback, which uses the algorithm for feature-vector (FV) dimension reduction, is described.
Radosavljević Vladan +7 more
doaj +2 more sources

