Results 201 to 210 of about 177,106 (269)

Alternatives to default shrinkage methods can improve prediction accuracy, calibration, and coverage: A methods comparison study. [PDF]

open access: yesStat Methods Med Res
van de Wiel MA   +5 more
europepmc   +1 more source

Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract FAALs (fatty acyl‐AMP ligases) recruit and incorporate fatty acids during the biosynthesis of secondary metabolites. Their diversity, distribution, and substrate specificity remain poorly understood, which limits functional predictions from sequence data.
Anne Liong   +2 more
wiley   +1 more source

A network-based model of Aspergillus fumigatus elucidates regulators of development and defensive natural products of an opportunistic pathogen. [PDF]

open access: yesNucleic Acids Res
Carriel CC   +10 more
europepmc   +1 more source

Fast, parallel, and cache-friendly suffix array construction [PDF]

open access: gold
Jamshed Khan   +4 more
openalex   +1 more source

Addressing Unwanted Morphodynamic Processes in Re‐Naturalization Projects

open access: yesRiver Research and Applications, Volume 42, Issue 2, Page 507-522, February 2026.
ABSTRACT River systems worldwide are undergoing severe ecological and morphological degradation due to prolonged anthropogenic interventions, such as channelization and dam construction, which disrupt sediment continuity and natural flow regimes. In response, river re‐naturalization projects have emerged as essential strategies to restore the dynamics ...
Lorenzo Durante   +2 more
wiley   +1 more source

Boosting Reversible Photocontrol of a Photoxenase by an Engineered Conformational Shift

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Photocontrol of enzymes with photoswitchable unnatural amino acids hitherto yielded only limited light‐regulation factors (LRFs). Here we boosted the LRF of an imidazole glycerol phosphate synthase variant from ∼15 to ∼100 in a semi‐rational design approach and unraveled the mechanistic fundamentals of this effect via biophysical and computational ...
Sabrina Mandl   +6 more
wiley   +2 more sources

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