Caracterização da Utilização de Sugamadex no Centro Hospitalar de Lisboa Central - Hospital de S. José [PDF]
Introdução O sugamadex é uma gama ciclodextrina modificada que forma um complexo com os bloqueadores neuromusculares rocurónio e vecurónio, revertendo o bloqueio neuromuscular (BNM) induzido por estes fármacos1,2,3,4.
Antas, T+4 more
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Sugammadex for Reversal of Neuromuscular Blocking Agents versus Neostigmine - Safety Comparison [PDF]
Purpose/Background Sugammadex and neostigmine are two common drugs used to reverse neuromuscular blockade in anesthesia, but they differ in mechanism of action, side effects, and cost. Sugammadex provides rapid reversal, has fewer side effects, and has a
Accardo, Bailey+5 more
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Selective reversal of muscle relaxation in general anesthesia: focus on sugammadex [PDF]
Despite the significant improvements in the pharmacology of muscle relaxants in the past six decades, the search for the ideal muscle relaxant continues, mainly because of the incomplete efficacy and persistent side effects associated with their ...
Brull, Sorin J, Naguib, Mohamed
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Sugammadex is a cyclodextrin specifically designed to reverse the action of rocuronium through encapsulation. Theoretically, it is possible that sugammadex can encapsulate cortisone. The primary outcome of the present study is to investigate any possible
Rabab Saber Saleh+1 more
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COMPARISON OF SUGAMMADEX WITH NEOSTIGMINE FOR REVERSAL OF VECURONIUM INDUCED NEUROMUSCULAR BLOCKADE: A RANDOMIZED CONTROLLED TRIAL [PDF]
Introduction: Neuromuscular blocking drugs (NMBDs) are commonly used in anesthesia, but residual neuromuscular blockade (RNMB) post-surgery can lead to serious complications such as hypoxia and airway obstruction.
Dr. Ayushi Dobhal, Dr. Neha Kathor, Dr. Seema Tikku Sharma, Dr. Anoop Negi, Dr. Ashutosh Singh
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The effect of magnesium on the reversal of rocuronium-induced neuromuscular block with sugammadex: an ex vivo laboratory study [PDF]
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Csernoch, Vera+4 more
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Neuromuscular Blockade Agents Reversal with Sugammadex Compared to Neostigmine in the Living Kidney Donors [PDF]
Backround: The reversation of NMBA (neuromuscular blocking agents) prevents numerous postoperative complications, increases quality of recovery and decreases the time, expenditure spending in hospital.
Chu, Dinh Toi+8 more
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Background Sugammadex is a pharmacologic agent that provides rapid reversal of neuromuscular blockade via encapsulation of the neuromuscular blocking agent (NMBA).
Sindhu N. Samba+5 more
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Evaluation of the effects of intra-arterial sugammadex and dexmedetomidine: an experimental study
Background: Intra-arterial injection of medications may cause acute and severe ischemia and result in morbidity and mortality. There is no information in the literature evaluating the arterial endothelial effects of sugammadex and dexmedetomidine.
Volkan Hancı+9 more
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Use of sugammadex in patients with neuromuscular disorders: a systematic review of case reports
Background Sugammadex is a modified gamma-cyclodextrin that acts by selectively encapsulating free amino-steroidal neuromuscular relaxants. Several case reports have been published on the use of sugammadex in patients with neuromuscular disorders that ...
Usha Gurunathan+2 more
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