Results 151 to 160 of about 544,105 (249)

Development of a Nursing Quality Evaluation Indicator System for Lung Cancer in Traditional Chinese Medicine Based on the Donabedian Model: A Delphi Study. [PDF]

J Multidiscip Healthc
Duan T, Liu Y, Wang H.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Mechanistic Explanations of Manual Therapy Do Not Influence Outcomes in Healthy Individuals: A Randomized Controlled Trial. [PDF]

Health Sci Rep
Waesch S, Leitner J, Stelzer LM, Adamczyk WM, Luedtke K, Szikszay TM.   +5 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Public Search Behavior and Tuberculosis Cases in Indonesia 2019-2023: An Infodemiology Study Using Google Trends . [PDF]

F1000Res
Rahayu SR, Merzistya ANA, Pranindita SK, Saharani A, Ardiyani VN, Muanifah EZ, Cahyati WH, Maharani C, Fandani DA, Widiastuti E, Daniswari A, Azizan NA.   +11 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Randomized Controlled Trial of Large Language Model-Assisted Diagnostic Accuracy in Nephrology. [PDF]

Kidney Int Rep
Bentegeac R, Le Guellec B, Maanaoui M, Gerard E, Amouyel P, Cheungpasitporn W, Florens N, Hamroun A.   +7 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Initiating a Life Skills Module to Prevent Drug Abuse Among Indonesian Adolescents Using Social Cognitive Theory [Response to Letter]. [PDF]

J Multidiscip Healthc
Utami YC, Rinawan FR, Sari P, Mutyara K, Herawati DMD.   +4 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source