Results 161 to 170 of about 486,598 (307)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Healing vs. hurting words: the power of language in pain perception-a narrative review. [PDF]

Front Pain Res (Lausanne)
Leonardi G, Bonanno F, Alito A, Stamile A, De Domenico C, Di Dio A, Sposito F, Cucinotta C, Tisano A, Portaro S.   +9 more
europepmc   +1 more source

La suggestion dans l’enseignement

, 1914
Derroja . La suggestion dans l’enseignement. In: La revue pédagogique, tome 65, Juillet-Décembre 1914. pp.
Derroja
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Enhancing radiology workflows through collaborative AI-assisted chest X-ray reporting using large vision-language models: a proof-of-concept study. [PDF]

Insights Imaging
Pellegrini C, Özsoy E, Gassert FT, Marka AW, Strenzke M, Keicher M, Makowski MR, Navab N.   +7 more
europepmc   +1 more source

A Suggestion [PDF]

The Musical Times
openaire   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Tips and tricks for addressing and responding to peer reviews. [PDF]

Conserv Physiol
Tomlinson S, Clements JC, Cooke SJ, Fuller A, O'Boyle B.   +4 more
europepmc   +1 more source

SUGGESTIBILITY AND HYSTERIA [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1943
openaire   +2 more sources