Results 181 to 190 of about 1,200,087 (341)
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Effects of suggestion therapy on mood and sleep quality in middle-aged women with depression. [PDF]
Jiang Y, Xia KK, Lin ZY.
europepmc +1 more source
An Address on the Deposition of the Crystalline Urates in the Tissues; Considered as a Separate Pathological Incident, with a Suggestion for a Distinctive Name [PDF]
William C. Roberts
openalex +1 more source
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
Development and validation of a self-management questionnaire for people living with HIV in low- and middle-income countries (HIV-SM LMIC tool). [PDF]
Dadi TL+3 more
europepmc +1 more source
OBSERVATIONS ON A CASE OF RUMINATION WITH SUGGESTIONS AS TO TREATMENT [PDF]
Martine Batchelor
openalex +1 more source
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy+12 more
wiley +1 more source
Trait responsiveness to verbal suggestions predicts nocebo responding: A meta-analysis. [PDF]
Stein MV+4 more
europepmc +1 more source