Results 41 to 50 of about 141,951 (260)
Risk of Self-Harm in Patients with Kleptomania: A Population-Based Cohort Study
Psychiatry InternationalBackground: This study investigated whether individuals with kleptomania (KTM) are at higher risk of engaging in self-harm behaviors than individuals without KTM.
Selina Kit Yi Chan +4 more
doaj +1 more source
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
Risk of self-harm in patients with body dysmorphic disorder: a population-based cohort study
Frontiers in PsychiatryObjectiveThis study was conducted to determine whether individuals with body dysmorphic disorder (BDD) have an increased risk of self-harm behaviors compared with those without BDD.MethodsIn this matched cohort study, we reviewed the electronic health ...
Wai Kwong Tang +5 more
doaj +1 more source
South African Journal of Psychiatry, 2022 Background: There is increasing evidence that patients with schizophrenia have high tendency to commit suicide. However, such an act is usually preceded by suicidal behaviours (or suicidality) such as suicidal ideations, suicidal intent, suicidal plans ...
Oluseun P. Ogunnubi +6 more
doaj +1 more source
Genetic Code Expanded T Cell for Controllable Immunotherapy
Advanced Science, EarlyView.Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang +4 more
wiley +1 more source
Oxidative stress parameters in women and men with suicidal thoughts and following a suicide attempt
Frontiers in PsychiatryBackgroundThis study aimed to evaluate oxidative stress parameters in individuals with depression and schizophrenia, considering gender differences, and manifesting suicidal behavior, encompassing thoughts without a tendency to be realized, thoughts with
Magdalena Lech +8 more
doaj +1 more source
What is special about suicidal depression?
European Psychiatry, 2021 Objective Bipolar disorder is one of the most frequent psychiatric disorders among suicidal patients. A large part of patients with bipolar disorder (30–50%) will attempt suicide.
P. Courtet, E. Olie
doaj +1 more source
Advanced Science, EarlyView.This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo +6 more
wiley +1 more source
The psychosocial toll of Dublin III on asylum seekers in the Netherlands
American Journal of Community Psychology, EarlyView.Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley +1 more source