Results 71 to 80 of about 13,211 (210)

The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle, Silvia Iñiguez‐Barrio, Maria Aurora Arrue, Leire Erkoreka   +3 more
wiley   +1 more source

The relationship among attachment styles, interpersonal needs, and suicidal ideation in patients with psychiatric disorders

Research in Psychotherapy
Suicide is a major public health concern; therefore, numerous factors have been investigated for their role in increasing suicide risk. Distal factors, such as attachment style, and proximal factors, like unmet interpersonal needs, interact with each ...
Salvatore Sarubbi, Elena Rogante, Denise Erbuto, Monica Migliorati, Isabella Berardelli, Marco Innamorati, Maurizio Pompili   +6 more
doaj   +1 more source

To What Extent Do Australian Government Metrics Align With Indigenous and Non‐Indigenous Conceptualisations of Wellbeing? A Scoping Review of Wellbeing Frameworks

Australian Journal of Social Issues, EarlyView.
ABSTRACT Indigenous wellbeing theories offer potential to better measure social and cultural determinants. This scoping review aimed to identify the types of metrics used by the Australian government to assess wellbeing and evaluate the alignment of current frameworks against Indigenous and non‐Indigenous conceptualisations of wellbeing.
Sophie Wright‐Pedersen, Edward J. O'Connor, Megan Rebuli, Tiana Thorne, Naomi Kakoschke, Ray Mahoney   +5 more
wiley   +1 more source

Suicide Mortality Across Broad Occupational Groups in Greece: A Descriptive Study

Safety and Health at Work, 2016
Background: Several studies have investigated the relationship between specific occupations and suicide mortality, as suicide rates differ by profession.
Evangelos C. Alexopoulos, Katerina Kavalidou, Fani Messolora   +2 more
doaj   +1 more source

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu, Weifeng Guo, Jianxiang Li, Tiange Zhang, Dan Xu   +4 more
wiley   +1 more source

Preoperative Risk Factors for Opioid Use Predict Self‐Reported Health and Function Up to 6 Months After Anterior Cruciate Ligament Reconstruction

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To identify risk factors that predict the need for rescue opioid use and patient‐reported outcomes following an opioid‐limiting postoperative analgesia protocol after anterior cruciate ligament reconstruction. Methods This prospective cohort study recruited 44 patients undergoing primary arthroscopic‐assisted anterior cruciate ligament ...
Eric V. Neufeld, William DeGouveia, Camille Pinpin, Matthew Zinner, Michael J. Sayegh, Michael J. Meade, Steven E. Rokito   +6 more
wiley   +1 more source

Patterns of acute poisoning cases at a high-altitude tertiary hospital in Nepal: a descriptive cross-sectional study

Journal of Karnali Academy of Health Sciences
Introduction: Poisoning, whether intentional or accidental, remains a significant public health issue in rural, high-altitude regions, with limited epidemiological data.
Robin Khapung, Subi Basnyat, Nabin Thapa, Bipin Luitel, lalit singh Dhami, Anita Thapa, Alan Pandey, Apil Adhikari, Praveen kumar Giri, Ramesh Bhattarai, Jeetendra Bhandari, Posan Samser Limbu, Sushil Gurung, Monika Lama, Kiran K.C, Prerana Shrestha, Sunika Banjade   +16 more
doaj   +1 more source

Adolescent substance use behavior and suicidal behavior for boys and girls: a cross-sectional study by latent analysis approach

BMC Psychiatry, 2017
Background Adolescent suicidal behavior may consist of different symptoms, including suicidal ideation, suicidal planning and suicidal attempts. Adolescent substance use behavior may contribute to adolescent suicidal behavior.
Peng-Wei Wang, Cheng-Fang Yen
doaj   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Psychological factors associated with suicide attempt and suicide death in Scotland: A systematic review

Journal of Affective Disorders Reports
Background: The identification of modifiable psychological factors associated with suicide attempt and suicide death is required for the development of effective preventive interventions.
Heather McClelland, Krystyna J Loney, Steve Platt   +2 more
doaj   +1 more source