Results 101 to 110 of about 30,495 (308)

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source

Identifying Unique Subgroups of Emotional and Behavioral Presentations in a Large Inpatient and Community Sample of Autistic Youth

Autism Research, EarlyView.
ABSTRACT Autistic youth exhibit wide variability in emotional and behavioral challenges, yet few studies have identified meaningful subgroups based on these profiles. This study applied a random forests ensemble clustering algorithm to item‐level parent‐report data from the Emotion Dysregulation Inventory (EDI) and the Child Behavior Checklist (CBCL ...
Safaa Eldeeb, Jessie Northrup, Caitlin Conner, Shalini Sivathasan, Ligia Antezana, Matthew Siegel, Carla Mazefsky   +6 more
wiley   +1 more source

The association of depression, impulsivity and suicidal ideation with organophosphate pesticide exposure amongst South African farm workers

, 2011
The objectives were to evaluate the validity and reliability of four neurobehavioral instruments used in the study and to test three models hypothesised as possible causal pathways between OP exposure and depression, impulsive behaviour and suicidal ...
Kootbodien, Tahira
core  

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Suicidal behaviours and associated factors among residents of Jimma Town, Southwest Ethiopia: a community-based cross-sectional study

BMJ Open
Introduction Suicidal behaviour is a major public health concern in Africa and a cause of premature mortality. The availability of community epidemiological data in Ethiopia is limited.
Elias Tesfaye, Selamawit Alemayehu Tessema, Alemayehu Negash Torba, Bezaye Alemu, Rachel Oblath   +4 more
doaj   +1 more source

Self-injury in Jail and suicidal behaviour

, 1990
SBN: CFI0275663 The AA. examine the evolution of the problem of self-harm and suicide conducted in the prisons of Modena from 1984 to 1988. In particular they emphasize how self-injury and suicide in prison reflect situations and motivations that are ...
DE FAZIO, Giovanna Laura, G. Gualandri
core  

Suicidal behavior among female sex workers in Goa, India: the silent epidemic. [PDF]

, 2009
OBJECTIVES: We sought to study suicidal behavior prevalence and its association with social and gender disadvantage, sex work, and health factors among female sex workers in Goa, India.
Copas, Andrew, Shahmanesh, Maryam, Wayal, Sonali, Mabey, David, Patel, Vikram, Cowan, Frances; id_orcid, Cowan, Frances   +6 more
core   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Definitions of Suicidal Behaviour

, 2004
Griffith Health, Australian Institute for Suicide Research & PreventionNo Full ...
Bille-Brahe, Unni, Kerkhof, Ad, Burgis, Shelley, De Leo, Diego, M. Bertolote, Jose   +4 more
core   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari, Caroline S. Copeland, Georgia C. Richards   +2 more
wiley   +1 more source