Results 111 to 120 of about 30,495 (308)

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria   +4 more
wiley   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval   +6 more
wiley   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou   +3 more
wiley   +1 more source

Imitation of Suicidal Behaviour

open access: yes, 2004
No Full ...
Schmidtke, Armin   +2 more
core  

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley   +3 more
wiley   +1 more source

Listening to Hong Kong children's perspectives through pretend play

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Quality in early childhood education and care (ECEC) has become an increasing concern in recent years. The issue has been regularly discussed by different stakeholders. However, the rising concern regarding quality in ECEC has not seriously taken into account children's perspectives.
Suzannie K. Y. Leung
wiley   +1 more source

Recall of early non-fatal suicidality in a nationally representative sample of South Africans

open access: yes, 2012
This is an Accepted Manuscript of an article published by Taylor & Francis in Ethnicity & Health on 1 March 2012, available online: http://www.tandfonline.com/10.1080/13557858.2012.664271.Objectives.
Van Pletzen, Ermien   +3 more
core  

Gender-related features of suicidal behaviour among the military in the Russo-Ukrainian war

open access: yes
The article identifies general and gender-specific features of suicidal behaviour among military personnel in the russo-Ukrainian war since 2014. The theoretical and methodological principles and results of research on suicidal behaviour are summarized ...
Martsenyuk T. O., Larkova Yu. S.
core   +1 more source

‘When joy comes your way, you have to grab it!’ Troubling how queer joy features in the lives of LGBT+ school‐attending youth in South Africa

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Recently, the concept ‘queer joy’ has gained interest in LGBT+ scholarship in the West. I use this scholarship as an entry point to explore how school‐attending LGBT+ youth express joy and how joy serves as a form of resistance against gender and sexuality norms in educational settings.
Dennis Francis
wiley   +1 more source

‘School is their whole world’: Teachers' perspectives on loneliness among children and adolescents from England and mainland China

open access: yesBritish Educational Research Journal, EarlyView.
Abstract As front‐line observers and active participants in pupils' daily lives, teachers closely monitor pupils' social interactions, emotional states and behavioural changes. Their unique perspective enables them to detect problems in the social lives of their pupils that may not be immediately visible to peers, parents or mental health professionals.
Yixuan Zheng   +4 more
wiley   +1 more source

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