Results 41 to 50 of about 115,506 (309)

Suicidal ideation among people with different gambling behaviour profiles: analysis of a longitudinal survey of people who gamble regularly in the UK

BJPsych Open
Background People who gamble experience elevated rates of suicidal thoughts and behaviours. Longitudinal studies have been scarce, and none has focused on those who regularly gamble in the UK.
Heather Wardle, Karen Wetherall, Jessica Wyllie, Sarah Tipping, Seonaid Cleare, Martin Jones, Sally McManus, Rory C. O’Connor   +7 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Profiling a set of personality traits of text author: what our words reveal about us [PDF]

, 2016
Authorship profiling, i.e. revealing information about an unknown author by analyzing their text, is a task of growing importance. One of the most urgent problems of authorship profiling (AP) is selecting text parameters which may correlate to an author ...
Litvinova, Olga, Litvinova, Tatiana, Seredin, Pavel, Zagorovskaya, Olga   +3 more
core   +2 more sources

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Psychological factors associated with suicide attempt and suicide death in Scotland: A systematic review

Journal of Affective Disorders Reports
Background: The identification of modifiable psychological factors associated with suicide attempt and suicide death is required for the development of effective preventive interventions.
Heather McClelland, Krystyna J Loney, Steve Platt   +2 more
doaj   +1 more source

Suicide death and hospital-treated suicidal behaviour in asylum seekers in the Netherlands: a national registry-based study

BMC Public Health, 2011
Background Several suicide and suicidal behaviour risk factors are highly prevalent in asylum seekers, but there is little insight into the suicide death rate and the suicidal behaviour incidence in this population. The main objective of this study is to
van Oostrum Irene EA, Stronks Karien, Kunst Anton E, Goosen Simone, Uitenbroek Daan G, Kerkhof Ad JFM   +5 more
doaj   +1 more source

Influence of Sex on Suicidal Phenotypes in Affective Disorder Patients with Traumatic Childhood Experiences. [PDF]

PLoS ONE, 2015
In the current study, we aimed to investigate the impact of childhood trauma on suicidal behaviour phenotypes in a group of patients with diagnosed affective disorder (unipolar or bipolar affective disorder).Patients with and without a history of ...
Alexandra Bernegger, Klemens Kienesberger, Laura Carlberg, Patrick Swoboda, Birgit Ludwig, Romina Koller, Nestor D Kapusta, Martin Aigner, Helmuth Haslacher, Michaela Schmöger, Siegfried Kasper, Alexandra Schosser   +11 more
doaj   +1 more source

Anxiety association with suicidal ideation or behaviour in individuals aged 18 – 49 years [PDF]

SHS Web of Conferences, 2020
Anxiety and suicide – closely related concepts, the understanding of which would contribute to the overall mental and physical health of society, and which is the basis for the successful development of any country.
Briede Ieva, Sudraba Velga
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Socio-demographic, psychosocial and environmental factors associated with suicidal behaviour in Indigenous Sami and Greenlandic Inuit adolescents; the WBYG and NAAHS studies

International Journal of Circumpolar Health, 2021
Background. For young Indigenous people, suicide is one of the leading causes of death, and high rates in Arctic areas indicate serious health- and societal concerns.
Ida Pauline Høilo Granheim, Anne Silviken, Christina Viskum Lytken Larsen, Siv Kvernmo   +3 more
doaj   +1 more source