Results 91 to 100 of about 187,058 (361)
Clinical Pharmacology &Therapeutics, EarlyView.Selective N‐methyl‐D‐aspartate receptor subunit 2b negative allosteric modulators (NR2B NAMs) are being explored as potential new treatment options for major depressive disorder (MDD). This Phase Ib, randomized, double‐blind, placebo‐controlled, parallel‐group trial was conducted in adults (N = 59) with moderate‐to‐severe MDD and insufficient response ...
Roger S. McIntyre +9 more
wiley +1 more source
Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization
Clinical Pharmacology &Therapeutics, EarlyView.Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su +6 more
wiley +1 more source
Why Young People With Eating Disorder Symptoms Do Not Seek Help—Exploring Barriers to Help‐Seeking
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Rates of help‐seeking and treatment uptake are low in eating disorders. Delayed initiation of treatment has a negative impact on prognosis and treatment outcome and leads to a higher burden on the healthcare system. The aim of this study was to explore factors associated with help‐seeking and their interactions in a large sample of ...
Johanna Stadler +46 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Background Focussed and programme‐led interventions have been of increased interest in the eating disorders (EDs) field as a potential solution to barriers in accessing timely, effective treatments. Little is known about the mechanisms through which these treatments work or for whom they are most suitable.
Daniel Wilson +2 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective The purpose of this pilot trial was to evaluate the novel use of Brief Behavioral Treatment for Insomnia (BBTI) for people with residual insomnia disorder following eating disorder (ED) treatment. Methods Participants (N = 6) completed a multiple‐baseline design study of BBTI.
Kara A. Christensen Pacella +4 more
wiley +1 more source
Insulin‐Related Disordered Eating Behavior: Clarifying Terminology
International Journal of Eating Disorders, EarlyView.ABSTRACT Objectives Consistent terminology for disordered eating behaviors relating to insulin manipulation is needed to consolidate and harmonize knowledge across research and practice. The aim of this study was to explore the terminology used to describe insulin‐related disordered eating behaviors in people with type 1 diabetes and suggest ...
Amy Shelford +2 more
wiley +1 more source
Evaluation of Three-Step Theory (3ST) of Suicide in Hospitalized Patients with Suicidal Ideation in Psychiatry Department of Shahid Yahya Nejad Hospital in Babol [PDF]
پزشکی بالینی ابن سیناBackground and Objective: Three-Stage Theory explains development of suicidal ideation and suicidal attempt. According to Three-Stage Theory, high levels of pain and high levels of hopelessness lead to suicidal ideation.
Alireza Azizi +4 more
doaj
International Journal of Eating Disorders, EarlyView.ABSTRACT Introduction The present study aims to examine predictors of dropout, treatment outcome, and relapse of web‐based guided self‐help cognitive behavior therapy‐enhanced (CBT‐E) for binge‐eating disorder. Data were collected as part of a randomized controlled trial examining the efficacy of guided self‐help CBT‐E.
Bernou Melisse +4 more
wiley +1 more source
Epileptic Disorders, EarlyView.Abstract Increasingly, it has been recognized that non‐seizure‐related factors influence how people with epilepsy perform on neuropsychological tests. Therefore, neuropsychologists need to recognize the constellation of factors that can contribute to the neurocognitive presentation of a person with epilepsy and consider these factors in the ...
Mary Lou Smith +12 more
wiley +1 more source
, 2021 Encyclopedia entry of suicidal ideation mechanism.
Tam-Tri Le, Minh-Hoang Nguyen
openaire +2 more sources