Results 51 to 60 of about 484,173 (338)

Suicide

The Lancet, 2009
Suicide receives increasing attention worldwide, with many countries developing national strategies for prevention. Rates of suicide vary greatly between countries, with the greatest burdens in developing countries. Many more men than women die by suicide.
Hawton, K, van Heeringen, K
openaire   +2 more sources

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Advanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen, Jiaqi Wu, Yuntong Li, Jiayu Huang, Xiangqin Weng, Jiale Wu, Shujun Xiao, Huaxin Song, Zhengyuan Wang, Ni Yan, Fangfang Shi, Derun Zheng, Kai Tan, Hesong Zhang, Jingyi Cui, Wen Wu, Wei Wu, Sujiang Zhang, Min Lu   +18 more
wiley   +1 more source

Spirituality and Religiosity during Suicide Bereavement: A Qualitative Systematic Review

Religions, 2021
A loved one’s loss to suicide can be a traumatic experience and trigger a difficult grief process, identity changes, a loss of the sense of meaning and a spiritual crisis.
Austėja Agnietė Čepulienė, Beata Pučinskaitė, Katryna Spangelytė, Paulius Skruibis, Danutė Gailienė   +4 more
doaj   +1 more source

Auxin‐Producing Pseudomonas Recruited by Root Flavonoids Increases Rice Rhizosheath Formation through the Bacterial Histidine Kinase Under Soil Drying

Advanced Science, EarlyView.
Drought is a major cause of crop losses across agricultural regions. Rhizosheath formation enhances plant resistance to drought. Polyploids may tolerate stress more effectively through increased interactions with bacteria. However, the contributions of tetraploid rice associated microbiota to rhizosheath formation under soil drying remain unclear ...
Feiyun Xu, Yongsen Wang, Jinyong Yang, Xue Zhang, Ke Wang, Fan Ding, Jiayin Pang, Lu Tong, Chuqi Bai, Shu Chen, Leyun Sun, Chongxuan Du, Ju Fang, Mengqiang Xu, Liang Li, Xin Yu, Jiahong Gengli, Jianping Liu, Qian Zhang, Zhengrui Wang, Yiyong Zhu, Huanyuan Zhang‐Zheng, Jianhua Zhang, Weifeng Xu   +23 more
wiley   +1 more source

Suicide after contact with substance misuse services: a national registry study

BJPsych Open, 2020
BackgroundPeople with substance use disorders have a well-known increased risk for taking their own life. Previous research has mainly focused on suicide in mental health services, whereas there is limited knowledge regarding suicide after contact with ...
Martin Ø. Myhre, Anine T. Kildahl, Fredrik A. Walby   +2 more
doaj   +1 more source

The EXPERIENCE system for the investigation of behavioral differences between depressed and healthy-control participants in Virtual Reality

European Psychiatry, 2023
Introduction The EXPERIENCE project aims to enable the creation and sharing of extended-personal realities in virtual reality (VR). Currently, software and hardware technology are under development, that will automatically generate VR environments based
S. Sutori, I. Todorov, G. Hadlaczky, V. Carli   +3 more
doaj   +1 more source

Suicide and Youth: Risk Factors

Frontiers in Psychiatry, 2018
Suicide occurs more often in older than in younger people, but is still one of the leading causes of death in late childhood and adolescence worldwide. This not only results in a direct loss of many young lives, but also has disruptive psychosocial and ...
J. Bilsen
semanticscholar   +1 more source

A Dual‐Targeting T6SS DNase Drives Bacterial Antagonism and Eukaryotic Apoptosis via the cGAS‐STING‐TNF Axis

Advanced Science, EarlyView.
The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song, Lei Xu, Pengfei Zhang, Shuying Li, Yichen Qu, Yixin Zhao, Zhenkun Shi, Ruiqi Ma, Yongdong Li, Yi Chen, Yao Wang, Zhengfan Jiang, Gehong Wei, Xihui Shen   +13 more
wiley   +1 more source

Cost-effectiveness of dialectical behaviour therapy vs. enhanced usual care in the treatment of adolescents with self-harm

Child and Adolescent Psychiatry and Mental Health, 2018
Background Studies have shown that dialectical behaviour therapy (DBT) is effective in reducing self-harm in adults and adolescents. Aims To evaluate the cost-effectiveness of DBT for adolescents (DBT-A) compared to enhanced usual care (EUC).
Egil Haga, Eline Aas, Berit Grøholt, Anita J. Tørmoen, Lars Mehlum   +4 more
doaj   +1 more source

Adaptation of evidence‐based suicide prevention strategies during and after the COVID‐19 pandemic

World Psychiatry, 2020
Suicide is preventable. Nevertheless, each year 800,000 people die of suicide in the world. While there is evidence indicating that suicide rates de‐crease during times of crises, they are expected to increase once the immediate crisis has passed.
D. Wasserman, M. Iosue, Anika Wuestefeld, V. Carli   +3 more
semanticscholar   +1 more source