Results 51 to 60 of about 405,279 (308)
Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy
Advanced Science, EarlyView.By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng +16 more
wiley +1 more source
A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control
Advanced Science, EarlyView.Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias +23 more
wiley +1 more source
Advanced Science, EarlyView.A recycling approach of spent lithium‐ion batteries is developed using brewing wastewater as the leaching agent and an engineering microbial consortium as the biocatalyst. Shewanella oneidensis reduces spent LiNixCoyMn1‐x‐yO2 cathodes via extracellular electron transfer, while Bacillus subtilis removes residual ethanol to eliminate inhibition.
Baocai Zhang +14 more
wiley +1 more source
Dying to Farm: Developing a Suicide Prevention Intervention for Farmers in Ireland
, 2023 Mental health problems and suicide are continually reported as major concerns for those actively employed in the Irish farming sector. Relative to other occupational groups, farmers experience a higher burden of health problems including mental ...
Russell, Tomás +3 more
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The psychosocial toll of Dublin III on asylum seekers in the Netherlands
American Journal of Community Psychology, EarlyView.Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley +1 more source
Injury Epidemiology, 2023 Background Rates of firearm suicide have increased among women Veterans. Discussing firearm access and reducing access to lethal means of suicide when suicide risk is heightened are central tenets of suicide prevention, as is tailoring suicide prevention
Evan R. Polzer +8 more
doaj +1 more source
HSE National Office for Suicide Prevention annual report 2020
, 2021 Annual report published by the HSE National Office for Suicide Prevention (NOSP), summarising its programme of work, expenditure, and details of funded services and initiatives from over 20 NGOs working in mental health and suicide ...
HSE National Office for Suicide Prevention (NOSP)
core
American Journal of Community Psychology, EarlyView.Abstract This study used photovoice methodology to explore Asian Americans' perspectives on the root causes and protective factors of firearm violence in their communities. Photovoice provided a participatory platform for community members to document lived experiences and identify priorities for change.
Tsu‐Yin Wu +4 more
wiley +1 more source
A suicide prevention initiative at a jumping site: A mixed-methods evaluation
EClinicalMedicine, 2020 Background: Gap Park in Sydney, Australia has historically been recognised as a suicide jumping site. In 2010–2011 the Gap Park Masterplan initiative implemented a series of suicide prevention measures.
Victoria Ross, Yu Wen Koo, Kairi Kõlves
doaj +1 more source