Results 81 to 90 of about 226,757 (260)

The impact of borderline personality disorder and sub-threshold borderline personality disorder on the course of self-reported and clinician-rated depression in self-harming adolescents

open access: yesBorderline Personality Disorder and Emotion Dysregulation, 2017
Background Studies on adults suggest that the presence of comorbid depression and Borderline Personality Disorder (BPD) is associated with an elevated risk of self-harming behaviours and that self-harming behaviours, when present, will have higher ...
Ruth-Kari Ramleth   +4 more
doaj   +1 more source

Emotional responses of veterinary students to first encounters with animal body donors

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Students' first encounters with animal body donors in higher education are a formative and also potentially stressful experience. The complex emotions elicited by body donor use in learning and their effects on professional development have been documented in medical students, but are far less explored in veterinary medical counterparts.
S. Regnault, C. Basu, S. Channon
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun   +4 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Geospatial estimates of suicidal ideation and suicide attempt prevalence in the U.S. veteran population (2022)

open access: yesInjury Epidemiology
Background Veteran suicide remains a major public health concern; rates increased 64.3% from 2001 to 2022 and substantial geospatial variation exists, with state-level rates ranging from 15.4/100,000 (Maryland) to 87.1/100,000 (Montana).
Julie A. Kittel   +6 more
doaj   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

Mixed-methods psychosocial autopsy study of suicide in young and middle-aged individuals in the Netherlands

open access: yesBMJ Public Health
Introduction Sociodemographic characteristics of suicide decedents are recorded in the Netherlands, through which we know who died by suicide, but not why.
Renske Gilissen   +8 more
doaj   +1 more source

Charcoal Burning and Maternal Filicide-Suicide Trends in Taiwan: The Impact of Accessibility of Lethal Methods

open access: yesJournal of the Formosan Medical Association, 2008
Charcoal burning has emerged as a novel suicide method in Taiwan and its impact on maternal filicide-suicide (MFS) remains unexplored. Using official national mortality data and reports of MFS cases from electronic newspaper archives, the authors aimed ...
Yi-Ju Pan, Ming-Been Lee
doaj   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria   +4 more
wiley   +1 more source

Rural-urban differences in post-9/11 women veterans’ firearm ownership and characteristics

open access: yesInjury Epidemiology
Background Access to firearms is associated with elevated risk for suicide; however, knowledge of firearm ownership and characteristics among rural residing women Veterans remains limited.
Ashley M. Griffith   +9 more
doaj   +1 more source

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