Results 51 to 60 of about 58,383 (262)

Masculinity and suicide attempt

Revista Latinoamericana de Estudios de Familia
Hegemonic masculinity, which emphasizes traits such as emotional stoicism and self-sufficiency has been shown to have a negative impact on men, especially in vulnerable groups such as adolescents, unemployed and/or homeless men and men with mental health
Teresita Morfín López, Luis Miguel Sánchez Loyo   +1 more
doaj   +1 more source

Suicide in hospitalized early psychosis patients at the time of discharge from hospital: An exploratory study of attempters and nonattempters

Indian Journal of Psychiatry, 2016
Background: Early intervention programs for psychosis are gateways for suicide prevention. These programs offer an excellent opportunity for prevention due to easy access, early identification, and provisions for continuity of care.
Amresh Shrivastava, Coralee Berlemont, Robbie Campbell, Megan Johnston, Avinash De Sousa, Nilesh Shah   +5 more
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Risk factors for violent suicide attempts: Hungarian cross-sectional study

European Psychiatry
Background Individuals who die by suicide tend to share more characteristics with those who attempt suicide using violent methods than with those who employ nonviolent means. To date, limited research has been published on the demographic characteristics
Noémi Szeifert, Lajos Bálint, Barbara Sebők, Xenia Gonda   +3 more
doaj   +1 more source

Empathy profiles differ by gender in people who have and have not attempted suicide

Journal of Affective Disorders Reports, 2020
Background: High levels of empathy may inhibit hetero-aggressive behaviors; however, the role of empathy on suicide behaviors is still unknown. This study aimed to compare the Interpersonal Reactivity Index (IRI) empathic profiles of 56 patients ...
Paolo Scocco, Emanuele Aliverti, Elena Toffol, Giuliana Andretta, Giovanna Capizzi   +4 more
doaj   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

The Epidemiologic Study of Suicide Attempt Referred to Hospitals of University of Medical Sciences in Markazi- Province from 2002 to 2006

مجله اپیدمیولوژی ایران, 2009
Background & Objectives: Suicide is considered as an important cause of death in many societies. Although many factors involve, there are inadequate information in this field.
M Rafiei, A Seyfi
doaj  

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, EarlyView.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Suicide and attempted suicide

Sri Lanka Journal of Psychiatry, 2014
Abstract not availableDOI: http://dx.doi.org/10.4038/sljpsyc.v5i2.7824Sri Lanka Journal of Psychiatry Vol 5(2):37 ...
Shehan S. Williams, Thilini Rajapakse
openaire   +3 more sources