Results 21 to 30 of about 83,910 (267)

A suicide prevention initiative at a jumping site: A mixed-methods evaluation

EClinicalMedicine, 2020
Background: Gap Park in Sydney, Australia has historically been recognised as a suicide jumping site. In 2010–2011 the Gap Park Masterplan initiative implemented a series of suicide prevention measures.
Victoria Ross, Yu Wen Koo, Kairi Kõlves
doaj   +1 more source

Women Veterans’ experiences discussing household firearms with their intimate partners: collaborative, devalued, and deferential relational types

Injury Epidemiology, 2023
Background Rates of firearm suicide have increased among women Veterans. Discussing firearm access and reducing access to lethal means of suicide when suicide risk is heightened are central tenets of suicide prevention, as is tailoring suicide prevention
Evan R. Polzer, Carly M. Rohs, Suzanne M. Thomas, Ryan Holliday, Christin N. Miller, Joseph A. Simonetti, Katherine M. Iverson, Lisa A. Brenner, Lindsey L. Monteith   +8 more
doaj   +1 more source

Sociodemographic and psychosocial risk factors of railway suicide: a mixed-methods study combining data of all suicide decedents in the Netherlands with data from a psychosocial autopsy study

BMC Public Health
Background Railway suicide has profound implications for the victims and their family, and affects train drivers, railway personnel, emergency services and witnesses.
Elias Balt, Saskia Mérelle, Arne Popma, Daan Creemers, Karlijn Heesen, Nikki van Eijk, Isa van den Brand, Renske Gilissen   +7 more
doaj   +1 more source

The EXPERIENCE system for the investigation of behavioral differences between depressed and healthy-control participants in Virtual Reality

European Psychiatry, 2023
Introduction The EXPERIENCE project aims to enable the creation and sharing of extended-personal realities in virtual reality (VR). Currently, software and hardware technology are under development, that will automatically generate VR environments based
S. Sutori, I. Todorov, G. Hadlaczky, V. Carli   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A mixed-methods evaluation of a large-scale online gatekeeper training to prevent youth suicides in the Netherlands

BMC Pediatrics
Background The increasing trend in suicides among young people emphasizes the urgent need for effective prevention strategies. Gatekeeper trainings (GKTs) equip individuals in a young person’s network with skills to recognize signs of suicidal thoughts ...
Paula von Spreckelsen, Natasha Waslam, Manon Merkus, Sanne Rasing, Sabine Jaken, Jeroen Steenmeijer, Renske Gilissen, Saskia Mérelle   +7 more
doaj   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Forecasting call and chat volumes at online helplines for mental health

BMC Public Health, 2023
Background Each year, many help seekers in need contact health helplines for mental support. It is crucial that they receive support immediately, and that waiting times are minimal. In order to minimize delay, helplines must have adequate staffing levels,
Tim Rens de Boer, Saskia Mérelle, Sandjai Bhulai, Renske Gilissen, Rob van der Mei   +4 more
doaj   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

The prevalence, course, and risk factors of suicidal ideation and suicide attempts among students in vocational education

Child and Adolescent Psychiatry and Mental Health
Background Worldwide, suicide is one of the leading causes of death among adolescents and young adults. Given that suicide in this age group is common within vocational students, this study aims to provide insights into the prevalence, course, and risk ...
Milou Looijmans, Paula von Spreckelsen, Guus Berkelmans, Arne Popma, Diana van Bergen, Renske Gilissen, Saskia Mérelle   +6 more
doaj   +1 more source