Results 61 to 70 of about 20,508 (261)

“Mo’ taca a met sü la pizza... Rabarbaro Zucca with un po‘ di BernasKäse” – Dialetto und Schweizerdeutsch im Vergleich

open access: yesBabylonia, 2018
Les dialectes apparaissent dans la publicité et animent la communication sur les réseaux sociaux: assiste-t-on à un renouveau du dialecte en Suisse italienne?
Matteo Casoni
doaj  

Transition vers la pratique infirmière et développement des compétences en sécurité des patients : protocole d’une étude longitudinale à méthodes mixtes

open access: yesScience of Nursing and Health Practices
Introduction : La première année d’exercice infirmier représente une période marquée par une vulnérabilité professionnelle, constituant un enjeu majeur pour la sécurité des soins.
Sylvain Boloré   +5 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

La Suisse urbaine : entre ubiquité et absence.

open access: yesEspacesTemps.net, 2004
Le regard porté sur le territoire suisse est aujourd'hui loin d'être univoque. D'un côté, l'image d'une Suisse urbaine diffusée par des chercheurs, des associations qui militent en faveur des villes et par les offices fédéraux de ...
Joëlle Salomon Cavin
doaj  

The usability issues of faceted navigation in digital libraries

open access: yesJLIS.it, 2014
The last decade transformed faceted navigation from a “nice-to-have” into a “must-have functionality” for all online web services that contain a search function.
Eliane Blumer   +2 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy