Results 151 to 160 of about 15,357,394 (325)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Assessing the potential and suitability of geothermal resources using Monte Carlo simulation and game-based combination weighting method

Meitian dizhi yu kantan
BackgroundGeothermal energy in porous sandstone reservoirs is recognized as stable, efficient clean energy. However, these reservoirs feature heterogeneity and exploration uncertainty, posing serious challenges to probabilistic resource assessment and ...
Yixiang HE, Pengpeng DING, Shaohua LIU, Mingzhu WANG, Lei ZHU   +4 more
doaj   +1 more source

Study on Quality Change and Processing Suitability Evaluation of the Low-Temperature Vacuum Frying of Bananas. [PDF]

Foods, 2023
Chen X, Tang Y, Wei Z, Deng Z, Li Z, Li L, He X, Sun J.   +7 more
europepmc   +1 more source

Evaluation of the Langley 4- by 7-meter tunnel for propeller noise measurements [PDF]

An experimental and theoretical evaluation of the Langley 4- by 7- Meter Tunnel was conducted to determine its suitability for obtaining propeller noise data. The tunnel circuit and open test section are described. An experimental evaluation is performed
Block, P. J. W., Gentry, G. L., Jr.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Suitability Assessment and Route Network Planning for Low-Altitude Transportation in Urban Agglomerations Using Multi-Source Data

Aerospace
As low-altitude transportation becomes essential to global integrated transport systems, developing extensive and well-structured networks in urban agglomerations is crucial for fostering regional synergy and enhancing three-dimensional transport ...
Jiayi Liu, Gaoru Zhu, Letong Yang, Yiling Shen   +3 more
doaj   +1 more source

Niche Suitability Evaluation and Path Selection for the High-Quality Development of Cities in the Yellow River Basin. [PDF]

Int J Environ Res Public Health, 2023
Shi P, Lu Z, Zhou M, Wang N, Wu Y.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Evaluation of soil suitability for organic agriculture

, 2018
The agrochemical soil properties are very important for determining fertility and suitability of soil for conventional and organic agricultural production. The aim of this study was to evaluate the suitability of the analyzed soil of eastern Croatia for organic agricultural production based on agrochemical soil properties.
Prpić, Dora, Gregić, Maja, Lončarić, Zdenko   +2 more
openaire   +3 more sources