Results 201 to 210 of about 23,309 (256)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hypertension acts together with Aβ pathology in late-life to promote memory loss. [PDF]

J Prev Alzheimers Dis
Da Ros LU, Ferrari-Souza JP, de Bastiani MA, Hauschild LA, Bellaver B, Ferreira PCL, Leffa DT, Povala G, Lussier FZ, Chamoun M, Bezgin G, Benedet AL, Rahmouni N, Macedo AC, Blennow K, Ashton N, Zetterberg H, Borelli WV, Souza DO, Pascoal TA, Rosa-Neto P, Zimmer ER, Alzheimer’s Disease Neuroimaging Initiative.   +22 more
europepmc   +1 more source

Presence of micro-mesoplastics in beaches and sediments of São Francisco do Sul (Brazil). [PDF]

Environ Monit Assess
Lopes-Ricardo ES, Martins AO, Rossa UB, Ribeiro EAW, Prado AR, Gomes EN, Radetski CM.   +6 more
europepmc   +1 more source

4‑Aminoalkylquinolines as Potent Antitubercular Agents Targeting the Cytochrome bc₁ Complex. [PDF]

ACS Med Chem Lett
Grams ES, Ramos AS, da Silva FF, Perelló MA, de Matos Czeczot A, Maia AM, Caetano HA, Altenhofen S, Paz JD, Gonçalves GA, Liu XG, Repasy T, Klein LD, Polesello GP, Sanchez Ferreira CA, de Oliveira SD, Stieler R, Silva SME, Bonan CD, Bizarro CV, Basso LA, Parish T, Machado P.   +22 more
europepmc   +1 more source

Phenotypic Detection Methods, Clinical Outcomes, and Therapeutic Strategies for OXA-Type Carbapenemase-Producing Acinetobacter Species in an Indian Tertiary Care Setting. [PDF]

Cureus
Ullengala PR, Shinde RV, Patil SR.
europepmc   +1 more source