Results 231 to 240 of about 618,368 (292)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Trachoma prevalence surveys in 15 indigenous and non-indigenous evaluation units in Brazil, 2018-2023. [PDF]

Int Health
Szwarcwald CL, Lopes MFC, de Souza Junior PRB, Gómez DVF, Luna EJA, de Almeida WDS, Damacena GN, Favacho JDFR, Medina NH, Franco Filho LC, Cogo A, Boyd S, Bakhtiari A, Jimenez C, Talero SL, Saboyá-Díaz MI, Solomon AW, Harding-Esch E.   +17 more
europepmc   +1 more source

Health and social policies to advance Brazil's End TB agenda during and after COVID-19: An analysis from tripartite governance and normative innovation perspectives. [PDF]

PLoS One
Ribeiro NM, Alexandre d'Auria de Lima MCR, Monroe AA, Vinci ALT, Vigato BF, Braga RS, Ferreira MRL, Caripa VCA, Rosa RJ, Zini N, Moura HSD, Bernardi WOB, Ballestero JGA, Palha PF, Andrade RLP, Arcêncio RA.   +15 more
europepmc   +1 more source

Prevalence, multidrug resistance patterns, virulence and antimicrobial resistance genes of emerging MDR Aeromonas hydrophila strains retrieved from subclinical bovine mastitis. [PDF]

Sci Rep
Algammal AM, Mabrok M, Almessiry BK, Alghamdi S, Alhindi Z, Sindi AS, Alenize M, Ghobashy MOI, Riad EM, Hamed AA, El-Tarabili RM.   +10 more
europepmc   +1 more source