Results 81 to 90 of about 23,309 (256)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Com a recente virada transnacional nas ciências humanas e sociais, as questões relacionadas ao translocalismo passaram a dominar a agenda acadêmica.
Isabel Hofmeyr
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Interrogar Diagnósticos no Sul Global
O presente artigo propõe uma análise crítica dos processos de elaboração e uso dos diagnósticos psiquiátricos a partir da perspectiva do Sul Global, situando-os como ferramentas historicamente atravessadas por normas hegemônicas, raciais, de gênero e capacitistas.
openaire +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Decolonizar o pensamento decolonial
O pensamento decolonial vem, na última década, tornando-se pujante no campo das ciências humanas no Brasil, sobretudo por meio da introdução de teorias produzidas pelo Grupo Modernidade/Colonialidade e por Boaventura de Sousa Santos.
Bruno dos Santos Joaquim
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Vozes do Sul: Pesquisas sobre as Epistemologias Alternativas no Sul Global
Este artigo propõe uma reflexão sobre as “vozes do Sul” (Pennycook, 2006) como formas de resistência epistemológica frente às dinâmicas de colonialidade que ainda atravessam a produção global de saberes. Inspirado pelas contribuições de Pennycook (2006), Sousa Santos (2010), Mignolo (2009), bell hooks (1994) e Anzaldúa (1987), o trabalho analisa como ...
openaire +1 more source

