Results 41 to 50 of about 13,129 (213)

Investigations of the antimicrobial activity of aminomethanesulfonic acids against strains of Staphylococcus aureus with different antimicrobial susceptibility

Zaporožskij Medicinskij Žurnal, 2019
One of the tasks of the WHO strategy against development of antibiotic resistance in microorganisms is the searching for new compounds with antimicrobial activity to develop new antimicrobial medicines.
T. L. Hrydina, R. Ye. Khoma, A. A.-A. Ennan, A. S. Fedchuk, O. A. Hruzevskyi   +4 more
doaj   +1 more source

Synthesis and Biological Evaluation of Novel Dihydro [2,3D] Pyridine Substituted Enaminosulfonamide Compounds as Potent Human Erythrocyte Carbonic Anhydrase II (hCAII)

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2021
Dihydro [2,3D] pyridine substituted enaminosulfonamide compounds have been synthesized and their effects on carbonic anhydrase II (hCAII) have been evaluated.
Tuna Demirci, Mustafa Oğuzhan Kaya, Mustafa Arslan, Oğuzhan Özdemir   +3 more
doaj   +1 more source

Ecotoxicological Insights From Ex Vivo Exposure of Whole Blood to PFOS and Glyphosate: Oxidative Stress and Immune Disruption

Environmental Toxicology, EarlyView.
ABSTRACT This study investigated the immunomodulatory effects of PFOS and glyphosate (GLY), both individually and in combination, on the whole blood of three ruminant species (cow, goats, and sheep) exposed ex vivo to environmentally relevant concentrations. The research focused on key biomarkers of oxidative stress (MDA), inflammation (myeloperoxidase
Francesco Molinari, Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Antonella Iaconis, Maria Rizzo, Giuseppe Piccione, Enrico Gugliandolo, Davide Di Paola   +8 more
wiley   +1 more source

OBTAINING AND APPLICATION OF SULFANILAMIDE MEDICINES [PDF]

, 2016
The method of sulfanilamide synthesis described in the article. The historical facts of discovery and application of sulfanilamide drugs are considered.
Haluzinska, Y.I., Siediuko, D.V., Геращенко, Ігор Іванович   +2 more
core  

Selective reaction of sulfanilamide with acetic anhydride catalyzed by stannous oxide nanoparticles [PDF]

شیمی کاربردی روز
Sulfonamide compounds with functional group -SO2NH- show a wide range of biological activities and medicinal properties. The synthesis of sulfonamides has been of interest to medicinal chemists for a long time. In this article, the selective acylation of
Maryam Ghazvinian, Nasrin Masnabadi, Mohammad Hadi Ghasemi, Javad Malakootikhah   +3 more
doaj   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

Environmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário, Deiweson Souza‐Monteiro, Walessa Alana Bragança Aragão, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Raquel Fernanda Gerlach, Antônio Hernandes Chaves‐Neto, Michael Aschner, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

Forward chemical genetic screens in Arabidopsis identify genes that influence sensitivity to the phytotoxic compound sulfamethoxazole

BMC Plant Biology, 2012
Background The sulfanilamide family comprises a clinically important group of antimicrobial compounds which also display bioactivity in plants. While there is evidence that sulfanilamides inhibit folate biosynthesis in both bacteria and plants, the ...
Schreiber Karl J, Austin Ryan S, Gong Yunchen, Zhang Jianfeng, Fung Pauline, Wang Pauline W, Guttman David S, Desveaux Darrell   +7 more
doaj   +1 more source

Blocking protein quality control degradation leads to structural stabilization of DHFR indel variants

The FEBS Journal, EarlyView.
Blocking protein quality control degradation by deleting the E3 ligases Ubr1 or San1 stabilizes many DHFR insertion and deletion variants that are otherwise partially unfolded. These hypomorphic variants regain folding at lower temperatures or upon methotrexate binding, revealing that PQC degradation can remove proteins that are still functionally ...
Sven Larsen‐Ledet, Caroline H. Suhr, Sarah Gersing, Celeste M. Hackney, Amelie Stein, Kaare Teilum, Rasmus Hartmann‐Petersen   +6 more
wiley   +1 more source

Non-acetylation of sulfanilamide during acquirement of drug resistance in Bacillus subtilis

, 1958
Cells of susceptible and sulfanilamide-resistant strains of Bacillus subtilis were harvested under various cultural conditions and examined for their ability, if any, to acetylate sulfanilamide. The effects of added acetate, citrate and accessory factors
Joshi, Sudha, Sreenivasan, A.
core   +1 more source

Simultaneous Determination of Sulfanilamide and Furosemide by Using Derivative Spectrophotometry

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
A simple, precise and accurate spectrophotometric method has been developed for simultaneous estimation of sulfanilamide and furosemide in their mixture by using first and second order derivative method in the ultraviolet region.
Samar A. Darweesh
doaj