Results 41 to 50 of about 24,499 (268)

Ecotoxicological Insights From Ex Vivo Exposure of Whole Blood to PFOS and Glyphosate: Oxidative Stress and Immune Disruption

Environmental Toxicology, EarlyView.
ABSTRACT This study investigated the immunomodulatory effects of PFOS and glyphosate (GLY), both individually and in combination, on the whole blood of three ruminant species (cow, goats, and sheep) exposed ex vivo to environmentally relevant concentrations. The research focused on key biomarkers of oxidative stress (MDA), inflammation (myeloperoxidase
Francesco Molinari, Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Antonella Iaconis, Maria Rizzo, Giuseppe Piccione, Enrico Gugliandolo, Davide Di Paola   +8 more
wiley   +1 more source

Selective reaction of sulfanilamide with acetic anhydride catalyzed by stannous oxide nanoparticles [PDF]

شیمی کاربردی روز
Sulfonamide compounds with functional group -SO2NH- show a wide range of biological activities and medicinal properties. The synthesis of sulfonamides has been of interest to medicinal chemists for a long time. In this article, the selective acylation of
Maryam Ghazvinian, Nasrin Masnabadi, Mohammad Hadi Ghasemi, Javad Malakootikhah   +3 more
doaj   +1 more source

Spin Crossover around Room Temperature: Effects of Remote Ligand Symmetry Breaking within Jäger‐Type Iron(II) Complexes

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Remote symmetry breaking in Jäger‐type iron(II) complexes shifts stepwise spin crossover (SCO) profiles to continuous profiles with transition temperatures around room temperature. In a bottom‐up approach, we studied the feedback of slight molecular modifications on the spin crossover (SCO) properties of otherwise structurally conserved iron(II ...
Florian Daumann, Lucie Gottwalt, Phil Köhler, Gerald Hörner, Birgit Weber   +4 more
wiley   +1 more source

Forward chemical genetic screens in Arabidopsis identify genes that influence sensitivity to the phytotoxic compound sulfamethoxazole

BMC Plant Biology, 2012
Background The sulfanilamide family comprises a clinically important group of antimicrobial compounds which also display bioactivity in plants. While there is evidence that sulfanilamides inhibit folate biosynthesis in both bacteria and plants, the ...
Schreiber Karl J, Austin Ryan S, Gong Yunchen, Zhang Jianfeng, Fung Pauline, Wang Pauline W, Guttman David S, Desveaux Darrell   +7 more
doaj   +1 more source

Genetic Studies of Sulfadiazine-resistant and Methionine-requiring \u3cem\u3eNeisseria\u3c/em\u3e Isolated From Clinical Material [PDF]

, 1967
Deoxyribonucleate (DNA) preparations were extracted from Neisseria meningitidis (four isolates from spinal fluid and blood) and N. gonorrhoeae strains, all of which were resistant to sulfadiazine upon primary isolation.
BROWN G. M., CATLIN B. W., CATLIN B. W., CATLIN B. W., CATLIN B. W., CAUTHEN S. E., DAVIS B. D., DAVIS B. D., DEMAIN A. L., DEMEREC M., E., DONALD I. J., DU VIGNEAUD V., W., EICKHOFF T. C., GRABOW W., HARRIS J. S., HATCH F. T., HOTCHKISS R. D., KAPLAN M. M., KATZEN H. M., KOHN H. I., LANDY M., LEDERBERG J., MILLAR J. W., OAKBERG E. F., PATO M. L., REYN A., REYN A., ROWBURY R. J., SICARD A. M., SINGER S., G., SMITH D. A., WILLCOX R. R., WINKLER K. C., WOLF B., WOODS D. D., WOODS D. D.   +35 more
core   +2 more sources

PbrIDD2‐PbrAPX14 Module Functions in the Ethylene‐Mediated Ripening and Senescence Process of Pear Fruit

Plant Biotechnology Journal, EarlyView.
ABSTRACT Endogenous H2O2 participated in the ethylene‐dependent ripening and senescence process of horticultural fruit as a secondary messenger; however, the molecular mechanism beneath such a phenomenon has not been fully clarified until recently. By a conjoint analysis of metabolite, enzyme activities, gene expression profiles in AsA‐GSH cycle of ...
Libin Wang, Junpeng Niu, Xiaoyu Tan, Yuhua Xie, Li Jiang, Chen Huan, Xu Zhang, Weiqi Luo, Bing Xie, Xiaopu Ren, Guodong Wang, Yuanyuan Guo, Shaoling Zhang   +12 more
wiley   +1 more source

Experimental Evolution of Magnetite Nanoparticle Resistance in Escherichia coli

Nanomaterials, 2021
Both ionic and nanoparticle iron have been proposed as materials to control multidrug-resistant (MDR) bacteria. However, the potential bacteria to evolve resistance to nanoparticle bacteria remains unexplored.
Akamu J. Ewunkem, LaShunta Rodgers, Daisha Campbell, Constance Staley, Kiran Subedi, Sada Boyd, Joseph L. Graves   +6 more
doaj   +1 more source

Three Dimensional Quantitative Structure-Activity Relationships of Sulfonamides Binding Monoclonal Antibody by Comparative Molecular Field Analysis [PDF]

, 2008
The three-dimensional quantitative structure-activity relationship (3D-QSAR) model of sulfonamide analogs binding a monoclonal antibody (MabSMR) produced against sulfamerazine, was carried out by comparative molecular field analysis (CoMFA).
Congming Wu, Haiyang Jiang, Jianzhong Shen, Linli Cheng, Ross C. Beier, Xingyuan Cao, Xinling Yang, Zhanhui Wang, Zhenpeng Kai   +8 more
core   +1 more source

Determination of Pharmaceuticals in Coastal Systems Using Solid Phase Extraction (SPE) Followed by Ultra Performance Liquid Chromatography – tandem Mass Spectrometry (UPLC-MS/MS) [PDF]

, 2015
This paper describes the optimization and validation of an analytical method for the determination of 83 pharmaceutically active compounds (PhACs) in aqueous samples using solid-phase extraction (SPE) followed by ultra performance liquid chromatography ...
Baena Nogueras, Rosa María, González Mazo, Eduardo, Lara Martín, Pablo Antonio, Pintado Herrera, Marina Guadalupe   +3 more
core   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source