Results 51 to 60 of about 11,867 (181)

Genotype‐Dependent Chemical Diversity and Bioactivity in Purple Elephant Grass: A Metabolomics‐Guided Evaluation for Animal Nutrition

Natural Sciences, Volume 6, Issue 4, October 2026.
ABSTRACT Purple elephant grass (Cenchrus purpureus (Schumach.) Morrone) is a valuable forage crop with potential bioactive properties that influence animal health. This study presents a comprehensive metabolomic characterization of two purple elephant grass genotypes (T441 and T515) using high‐resolution mass spectrometry (HRMS), molecular networking ...
Salva Asghar, Erica A. Batista, Eric de Souza Gil, Gracimerio José Guarneire, Ana Mara F. Nunes, Sandra B. R. de Castro, Alessandra P. Carli, Caio César S. Alves, Juarez C. Machado, Abeer M. Alawi Al‐Sakkaf, Teresinha J. A. S. Andrade, Danielle F. Dias, Marisi G. Soares, Nerilson M. Lima   +13 more
wiley   +1 more source

Neuroprotective Effects of Senecio brasiliensis Extract Against Chlorpyrifos‐Induced Neurotoxicity and Oxidative Stress in Drosophila melanogaster

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Chlorpyrifos (CP) is an organophosphate insecticide that induces neurotoxicity through acetylcholinesterase (AChE) inhibition and redox imbalance, raising environmental and occupational health concerns. Plant‐derived compounds from Senecio brasiliensis, native to the Pampa biome, offer multitarget therapeutic potential.
Maria Vitória Takemura Mariano, Giany Gabriely Padão dos Santos, Ana Beatriz Guedes de Souza, Thaís de Camargo Neves, Franklin Vinny Medina Nunes, Pedro Henrique Vicenzi, Karen Kich Gomes, Mauro Eugênio Medina Nunes, Marcelo Farina, Jeferson Luis Franco, Thaís Posser   +10 more
wiley   +1 more source

Novel essential amino acid-sulfanilamide hybrid as safe anti-ulcerogenic agent with anti-helicobacter pylori activity

Saudi Pharmaceutical Journal, 2017
A novel and safe essential amino acid (Leucine) incorporating sulfanilamide was synthesized, and evaluated for its anti-ulcerogenic activity and in vitro anti-Helicobacter pylori activity.
Amani S. Awaad, Ahmed M. Alafeefy, Fatmah A.S. Alasmary, Reham M. El-Meligy, M.E. Zain, Saleh I. Alqasoumi   +5 more
doaj   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, Volume 38, Issue 47, 21 August 2026.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Electrochemical Reduction of Nitrate to Ammonia on Transition‐Metal Sputtered Copper Foams

ChemElectroChem, Volume 13, Issue 15, 1 August 2026.
Thin, sputter‐deposited cobalt layers on copper foam significantly enhance electrochemical reduction of nitrate to ammonia, exhibiting an approximately threefold increase in Faradaic efficiency for ammonia, likely due to a synergistic two‐step conversion pathway involving both copper and cobalt sites.
Sabita Bhandari, Nick Hausen, Xin Wei, Michael Noyong, Regina Palkovits, Ulrich Simon   +5 more
wiley   +1 more source

Metabolite‐Driven Biological Activity of Mandragora autumnalis and Spartium junceum: A Comparative LC‐MS/MS Study on Antioxidant, Cholinesterase, and Carbonic Anhydrase Inhibition

ChemistryOpen, Volume 15, Issue 8, August 2026.
Low‐molecular‐weight phenolic acids in M. autumnalis were associated with antioxidant activity, AChE, and hCA inhibition effects, whereas flavonoid‐rich S. junceum displayed BChE‐oriented inhibition effect and antibacterial activity. LC‐MS/MS‐based metabolite profiling linked distinct chemical compositions to bioactivity patterns, supporting further ...
Kubra Aslan, Esra Elbir, Yusuf Bicakci, Silanur Ozdogan, Mustafa Abdullah Yilmaz, Ilhami Gulcin   +5 more
wiley   +1 more source

PbrIDD2‐PbrAPX14 Module Functions in the Ethylene‐Mediated Ripening and Senescence Process of Pear Fruit

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4878-4896, August 2026.
ABSTRACT Endogenous H2O2 participated in the ethylene‐dependent ripening and senescence process of horticultural fruit as a secondary messenger; however, the molecular mechanism beneath such a phenomenon has not been fully clarified until recently. By a conjoint analysis of metabolite, enzyme activities, gene expression profiles in AsA‐GSH cycle of ...
Libin Wang, Junpeng Niu, Xiaoyu Tan, Yuhua Xie, Li Jiang, Chen Huan, Xu Zhang, Weiqi Luo, Bing Xie, Xiaopu Ren, Guodong Wang, Yuanyuan Guo, Shaoling Zhang   +12 more
wiley   +1 more source

Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed‐Culture Ferment Extract by Tripeptide GHK‐Cu

Skin Research and Technology, Volume 32, Issue 8, August 2026.
ABSTRACT Background Skin aging is a complex process driven by multiplex factors, including chronic inflammation and UV exposure. It has become common practice for cosmetic formulations to counteract skin aging by targeting different pathways simultaneously with a pool of active ingredients.
Jingyi Wang, Kan Tao, Hu Huang, Huailong Chang   +3 more
wiley   +1 more source

Spectrophotometric Determination of Ceftiofur Hydrochloride Using N-Bromosuccinimide and p-Dimethylaminobenzaldehyde

E-Journal of Chemistry, 2009
Simple, accurate and reproducible UV-Visible spectrophotometric methods were established for the assay of ceftiofur based on the formation of oxidation and condensation products.
V. Annapurna, G. Jyothi, C. Rambabu, B. B. V. Sailaja   +3 more
doaj   +1 more source

SYNTHESIS AND SPECTROSCOPIC STUDY OF SOME COORDINATIVE COMPOUNDS OF Co(III), Ni(II) AND Cu(II) WITH DIANILINE- AND DISULFANILAMIDEGLYOXIME [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2011
Directed synthesis of dianiline- (DAnH2) and disulfanilamideglyoximes (DSamH2) has been accomplished by condensation of dichloroglyoxime with aniline or sulfanilamide in 1:2 molar ratio, as well as their corresponding Co(III), Ni(II) and Cu(II ...
Andrei Rija, Ion Bulhac, Eduard Coropceanu, Elena Gorincioi, Elena Calmîc, Alic Barbă, Olga Bologa   +6 more
doaj