Results 81 to 90 of about 3,260 (184)

Sulfasalazine: Dissolution and Distribution in Pharmaceutically Relevant Mediums

, 2016
The sulfasalazine melting temperature and molar enthalpy have been determined by the DSC method. The shake flask method has been used to measure the drug solubility in buffer solutions (pH 2.0 and 7.4), hexane, and octanol and to determine the ...
Marina V. Ol’khovich (1995505), Svetlana V. Blokhina (2169601), German L. Perlovich (1497871), Angelica V. Sharapova (1995502)   +3 more
core   +1 more source

Successful Treatment of Severe Adult Linear IgA Dermatosis Using Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Linear IgA dermatosis (LAD) is a rare autoimmune subepidermal bullous dermatosis, characterised by the presence of erythematous vesiculobullous lesions arranged in rosettes or herpetiform clusters. The standard treatment involves the administration of dapsone, followed by sulfasalazine, and general corticosteroid therapy, often in combination ...
Célia Delesalle, Claire Abasq‐Thomas, Claire Bocciarelli, Amélie Bourhis, Marina Alexandre, Belen Eguia, Laurent Misery, Numa Deydier   +7 more
wiley   +1 more source

Sulfasalazine in Prevention of Pouchitis After Proctocolectomy with Ileal Pouch–Anal Anastomosis for Ulcerative Colitis

, 2017
Background: Pouchitis is the most frequent complication after ileal pouch–anal anastomosis for refractory ulcerative colitis. A non-standardized preventative treatment exists. Sulfasalazine has proved effective in acute pouchitis therapy.
SCAIOLI, ELEONORA, SARTINI, ALESSANDRO, BELLUZZI, ANDREA, ROSATI, GIANCARLO, FESTI, DAVIDE, Digby, Richard John, POGGIOLI, GILBERTO, LIVERANI, ELISA, BAZZOLI, FRANCO, UGOLINI, GIAMPAOLO   +9 more
core   +1 more source

Drug reaction with eosinophilia and systemic symptoms (dress) syndrome associated with sulfasalazine without eosinophilia

Sri Lanka Journal of Medicine, 2019
A 28-year-old previously healthy woman presented with fever and constitutional symptoms for one week duration. Prior to the hospital admission, she had been treated for an inflammatory arthritis with sulfasalazine for three months duration.
K. S. Hettiarachchi, M. M. Ranasinghe, S. Pirasath, A. G. H. Sugathapala   +3 more
doaj   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, EarlyView.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Literature review of the clinical features of sulfasalazine-induced drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivity syndrome (DRESS/DIHS)

Frontiers in Pharmacology
BackgroundSulfasalazine (SSZ) is commonly prescribed for the treatment of ulcerative colitis, rheumatoid arthritis, and ankylosing spondylitis. However, it can also trigger a severe drug reaction known as Drug Reaction with Eosinophilia and Systemic ...
Ya Liu, Danxia Wang, Shiwei Wu, Xiang Liu, Can Xiao   +4 more
doaj   +1 more source

Effects of baicalein on protein expression of Th1/2 cells, obestatin and 5-hydroxytryptamine in rats with ulcerative 

Zhongguo linchuang yanjiu
Objective To investigate the effects of baicalein on T helper cells (Th) 1/2, obestatin and 5-hydroxytryptamine (5-HT) in rats with ulcerative colitis.
KUANG Zhe, GUO Huili, ZHANG Yongchao, MIAO Zhiwei   +3 more
doaj   +1 more source

IN-VIVO PHARMACOKINETIC STUDIES OF SULFASALAZINE SOLID LIPID NANOPARTICLES

Nanoparticles, particularly Solid Lipid Nanoparticles (SLNs), are increasingly utilized as efficient drug delivery systems due to their ability to enhance bioavailability, provide controlled release, and improve drug stability.
Hema Devi Tumma, Praveena Chinthala
core   +1 more source

Comparison of the effects of Tripterygii totorum and sulfasalazine on rheumatoid arthritis: A retrospective cohort study

, 2020
Purpose: To compare, in a retrospective study, the effects and safety profiles of Tripterygii totorum and sulfasalazine in patients with rheumatoid arthritis (RA) following 24 weeks of treatment.
Zeng, Jiali, Tang, Yongliang, Huang, Renchun   +2 more
core   +1 more source