Results 61 to 70 of about 207,102 (294)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Bioaugmentation of UASB reactors with immobilized Sulfurospirillum barnesii for simultaneous selenate and nitrate removal [PDF]

, 2009
Whole-cell immobilization of selenate-respiring Sulfurospirillum barnesii in polyacrylamide gels was investigated to allow the treatment of selenate contaminated (790¿µg Se¿×¿L-1) synthetic wastewater with a high molar excess of nitrate (1,500 times) and
Aelst, A.C., van, Enright, A.M., Lens, P.N.L., Lenz, M., O’Flaherty, V.   +4 more
core   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Usage of metals as the terminal electron acceptors by the sulfate-reducing bacteria

Біологічні студії, 2009
The review briefly describes the toxic effects of heavy metals towards microorganisms and the resistance mechanisms to heavy metals. The processes of fermentative and non-fermentative reduction of oxidized metals forms by the sulfate-reducing bacteria ...
T. B. Peretyatko, A. A. Halushka, S. P. Gudz   +2 more
doaj   +1 more source

Transcriptomic and proteomic analyses of Desulfovibrio vulgaris biofilms: carbon and energy flow contribute to the distinct biofilm growth state. [PDF]

, 2012
BackgroundDesulfovibrio vulgaris Hildenborough is a sulfate-reducing bacterium (SRB) that is intensively studied in the context of metal corrosion and heavy-metal bioremediation, and SRB populations are commonly observed in pipe and subsurface ...
Arkin, Adam P, Clark, Melinda E, Fields, Matthew W, He, Zhili, Joachimiak, Marcin P, Keasling, Jay D, Mukhopadhyay, Aindrila, Redding, Alyssa M, Zhou, Jizhong Z   +8 more
core   +3 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Aerobic respiration in sulfate-reducing bacteria [PDF]

FEMS Microbiology Letters, 1990
Cultures of Disulfovibrio desulfuricans strain CSN (incubated in a sulfide- and sulfate-free medium) reduced up to 5 mM O2 with H2 as electron donor. Aerobic respiration was not coupled with growth, but resulted in ATP formation. Washed cells incubated in H2-saturated phosphate buffer revealed respiration rates of up to 250 nmol O2 min−1 mg protein−1 ...
Waltraud Dilling, Heribet Cypionka
openaire   +2 more sources

Evidence of microbial activity from a shallow water whale fall (Voghera, northern Italy) [PDF]

, 2012
The fossil bones, associated carbonate cements and enclosing concretion of a Miocene mysticete from inner shelf deposits (Monte Vallassa Formation, northern Italy) were analyzed for evidence of microbial activity. Optical and scanning electron microscopy,
Cavalazzi, B, Danise, S, Dominici, S, Guioli, S, Monechi, S, Westall, F   +5 more
core   +4 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Control of Microbial Sulfide Production with Biocides and Nitrate in Oil Reservoir Simulating Bioreactors.

Frontiers in Microbiology, 2015
Oil reservoir souring by the microbial reduction of sulfate to sulfide is unwanted, because it enhances corrosion of metal infrastructure used for oil production and processing. Reservoir souring can be prevented or remediated by the injection of nitrate
Yuan eXue, Gerrit eVoordouw
doaj   +1 more source