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In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu +7 more
wiley +1 more source
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
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This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang +12 more
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ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang +11 more
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This study employs a nanochain engineering approach combined with an in situ oxidation strategy to fabricate self‐insulating iron‐based magnetic nanochains, addressing the challenge of balancing magnetic coupling and electrical insulation in soft magnetic materials.
Dingrong Zuo +8 more
wiley +1 more source
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Electron donors for biological sulfate reduction
Biotechnology Advances, 2007Biological sulfate reduction is widely used for treating sulfate-containing wastewaters from industries such as mining, tannery, pulp and paper, and textiles. In biological reduction, sulfate is converted to hydrogen sulfide as the end product. The process is, therefore, ideally suited for treating metal-containing wastewater from which heavy metals ...
Warounsak, Liamleam, Ajit P, Annachhatre
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The antiquity of microbial sulfate reduction
Earth-Science Reviews, 2004The phylogenetic positions of sulfate-reducing organisms, as revealed from comparisons of small-subunit ribosomal RNA (SSU rRNA), are spread over both the Archaeal and Bacterial domains, though when they evolved is uncertain. The low-branching positions of some of these groups on the Tree of Life have inspired the hypothesis that the metabolic ...
Yanan Shen, Roger Buick
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Sulfate Reduction in Marine Sediments
2000The present chapter deals with the biogeochemical transformations of sulfur within marine sediments during early diagenesis. The term ‘early diagenesis’ refers to the whole range of postdepositional processes that take place in aquatic sediments coupled either directly or indirectly to the degradation of organic matter.
Kasten, S., Jørgensen, B.
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Reduction of sulfates by hydrogen
Canadian Journal of Chemistry, 1976The initial stage of reduction of anhydrous sulfates by H2 may lead to the formation of any of the following: (1) sulfates at lower valency, e.g., reduction of CuSO4, HgSO4, Fe2(SO4)3; (2) metals, e.g., Cu2SO4, Ag2SO4; (3) sulfides, e.g., NiSO4, CoSO4, CdSO4, CaSO4, SrSO4, BaSO4, and alkaline metal sulfates; (4) oxides, e.g., Al2(SO4)3, MgSO4, BeSO4; (
Fathi Habashi +2 more
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