Results 41 to 50 of about 26,681 (248)

Intrinsic emission and electron-hole trapping centers in crystals Li2SO4-Cu

Eurasian Journal of Physics and Functional Materials, 2021
In the present work, the emission and excitation spectra in Li2SO4-Cu crystals have been obtained by the methods of vacuum-ultraviolet and thermoactivation spectroscopy.
T.N. Nurakhmetov, Zh.M. Salikhodzha, M.Y. Dolomatov, B.N. Yussupbekova, A.M. Zhunusbekov, A.Zh. Kainarbay, D.H. Daurenbekov, B.M. Sadykova, K.B. Zhangylyssov, T.T. Alibay, D.A. Tolekov   +10 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

QUANTITATIVE DYNAMISM OF CHEMICAL COMPOSITION INDICATORS AS A MARKER OF QUALITATIVE GROUNDWATER DIFFERENTIATION (ON THE EXAMPLE OF SYNYCHAN WATER INTAKE)

Геохімія техногенезу, 2021
The article presents the physical and geographical characteristics of the Synychan water intake section of the Izium water intake, which is located 8 km southeast of the city of Izium, Kharkiv region.
I. Udalov,, D. Piatash
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Total Dissolved Solids (TDS) Less Than 1000 ppm in Drinking Water Did Not Impact Nursery Pig Performance

Veterinary Sciences, 2022
High concentrations of total dissolved solids (TDS) in water have been reported to increase the incidence of diarrhea and reduce nursery pig growth performance.
Ryan Samuel
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

BALKAN YARIMADASI'NDA JEOLOJİK ZAMAN BOYUNCA SÜLFÜR

Bulletin of the Mineral Research and Exploration, 2002
Uzun bir dönemdir yürütülmekte olan araştırmalarda Balkan Yarımadasındaki en yaşlı metalojenik evrelerin, ana kimyasal elementlerden biri olan sülfürü içeren oluşukları sınırlı sayıda kapsadığı belirlenmiştir. Bu nedenle de.
Radule POPOVİC
doaj  

Subsurface Microbial Ecology at Sediment-Groundwater Interface in Sulfate-Rich Playa; White Sands National Monument, New Mexico

Frontiers in Microbiology, 2019
The hypersaline sediment and groundwater of playa lake, Lake Lucero, at the White Sands National Monument in New Mexico were examined for microbial community composition, geochemical gradients, and mineralogy during the dry season along a meter and a ...
Mihaela Glamoclija, Steven Ramirez, Kosala Sirisena, Kosala Sirisena, Kosala Sirisena, Inoka Widanagamage, Inoka Widanagamage   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Orthogonal Sulfation Strategy for Synthetic Heparan Sulfate Ligands. [PDF]

ChemInform, 2005
[reaction: see text] An orthogonal sulfation strategy involving six different protecting groups has been developed for generating sulfated carbohydrate libraries based on heparan. Chemoselective cleavage conditions (optimized for a heparan disaccharide) can be performed in the presence of sulfate esters as well as the remaining protecting groups.
Ren-Hua, Fan, Jihane, Achkar, Jesús M, Hernández-Torres, Alexander, Wei   +3 more
openaire   +3 more sources