Summary Pneumolabyrinth, which is the presence of gas within the labyrinth of the inner ear, can be associated with severe peripheral vestibular signs. This report describes a case of pneumolabyrinth in a horse that presented with vestibular ataxia. An 8‐year‐old Quarter Horse mare that presented with cranial nerve VII deficits underwent a standing ...
C. A. Jamieson +5 more
wiley +1 more source
Small Molecule Drug Conjugate Hybrids of Naphthalene Sulfonamide and Phospholipid Conjugates Are Microtubule-Disrupting Antitumor Agents. [PDF]
Fernández-Ceballos N +2 more
europepmc +1 more source
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura +6 more
wiley +1 more source
Engineering a smart multifunctional UiO-66(Zr)-based metal-organic framework for simultaneous nutrient monitoring and water remediation <i>via</i> spectrophotometric sensing, adsorption, Box-Behnken design, machine learning, and DFT analysis. [PDF]
Alnahdi KM +7 more
europepmc +1 more source
ABSTRACT Monitoring antimicrobial resistance (AMR) in fish pathogens is essential for supporting sustainable aquaculture. In this study, susceptibility testing and genome sequencing were used to characterize the AMR profile of seven Flavobacterium psychrophilum originating from Danish rainbow trout farms (2019–2022).
Valentina L. Donati, Lone Madsen
wiley +1 more source
Design, synthesis and network pharmacology-integrated evaluation of benzenesulfonamides as potential Dickkopf-1 (Dkk-1)-targeting anticancer candidates. [PDF]
Ejaz SA +8 more
europepmc +1 more source
ABSTRACT In February 2025, a mortality event of unknown aetiology occurred at a hybrid grouper (Epinephelus fuscoguttatus × Epinephelus lanceolatus) aquaculture farm in southern Taiwan, with sporadic daily deaths persisting for a month. Four moribund groupers were collected over three sampling intervals for diagnostic investigation.
Shang‐Ting Wu +2 more
wiley +1 more source
Biocatalytic reduction of nitro-sulfonamides: enzyme engineering, process integration, and sustainable pathways to <i>p</i>-aminobenzenesulfonamide. [PDF]
Ai R +8 more
europepmc +1 more source
ABSTRACT Trimethoprim (TMP)‐sulfonamide combinations are widely used in veterinary medicine, yet the quantitative nature of their pharmacodynamic interaction remains incompletely characterised. This study investigated the interaction between TMP and sulfamethoxazole (SMX), sulfadiazine (SDZ) and sulfadimethoxine (SDMX) against two Staphylococcus ...
Andrew Mead +7 more
wiley +1 more source
Discovery and synthesis of phenylthiophene sulfonamide derivatives with promising anti-inflammatory activity. [PDF]
Dai Z +10 more
europepmc +1 more source

