Catalytic enantioselective synthesis of α-C chiral sulfones enabled by merging photoactive electron donor-acceptor complexes with nickel catalysis. [PDF]
Lai ZM, Xie Y, Huang LL, Guo J, Lu G.
europepmc +1 more source
Structure-reactivity based control of radical-mediated degradation in thiol-Michael hydrogels.
Kirkpatrick BE +7 more
europepmc +1 more source
Expanding the Crosslinking Mass Spectrometry Toolbox With Vinyl Sulfone Crosslinkers. [PDF]
Ciancone A +8 more
europepmc +1 more source
Aryl and Alkyl Radiotrifluoromethylation via Metallaphotoredox‐Mediated Radical Cross‐Coupling
The metallaphotoredox‐mediated radiotrifluoromethylation of arenes and alkanes is described. The operationally simple protocols make use of substrates bearing thianthrenium salts (TT) or N‐hydroxyphthalimide (NHPI) esters and CF218FI. The reaction proceeds through a Ru‐mediated radical formation followed by a Cu‐mediated radical cross‐coupling step and
Lukas Veth +2 more
wiley +2 more sources
General Modular and Convergent Approach to Diversely Functionalized Allylic Systems. [PDF]
Giri S, Kvasovs N, Gevorgyan V.
europepmc +1 more source
Regiodivergent C3 and C4 Amination of Quinolines via Radical and Ionic Pathways
A regiodivergent strategy converts a single N‐aminoquinolinium precursor into either C3‐ or C4‐aminated quinolines. Nucleophile‐induced dearomatization diverges into light‐driven N‐centered radical capture (C3) or base‐promoted SNAr (C4), enabling rapid assembly of aminoquinoline libraries and late‐stage diversification.
Ye‐Eun Kim +3 more
wiley +2 more sources
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich +11 more
wiley +1 more source
Application of a MALDI mass spectrometry assay to identify covalent fragments targeting the methyl-lysine reader protein MPP8. [PDF]
Rubiano JLS +7 more
europepmc +1 more source
Potassium <i>tert</i>-Butoxide-Mediated Isomerization of Alkenes: A Versatile Protocol for Miscellaneous Substrates. [PDF]
Heras Martínez HM +6 more
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Importance of S-Doped Porous Carbon Acidity and Visible Light Photoactivity for Its Antibacterial Activity. [PDF]
Sadikaj D +13 more
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