Using Pharmacoepidemiology to Examine the Interplay of Sulfonylureas and Infection Risk in Patients With Diabetes Mellitus. [PDF]
CPT Pharmacometrics Syst PharmacolWu YY +4 more
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Diagnosis and Treatment of Neonatal Diabetes Caused by ATP-Channel Mutations: Genetic Insights, Sulfonylurea Therapy, and Future Directions. [PDF]
Children (Basel)Trada M +5 more
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Hypoglycemic and Hypolipidemic Effects of <i>Leonotis mollisima</i> Aqueous Leaf Extract in Type 2 Diabetic Rats. [PDF]
J Exp PharmacolStephen N +4 more
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Hyponatremia Due to Sulfonylurea Compounds
The Journal of Clinical Endocrinology & Metabolism, 1970ABSTRACT In a 68-yr-old female with diabetes mellitus and idiopathic cerebral atrophy, therapeutic doses of chlorpropamide or tolbutamide induced a hyponatremic syndrome identical with that of inappropriate secretion of ADH (serum Na 117 mEq/1). Metabolic studies revealed that the hyponatremia was due in part to negative sodium balance.
G A, Hagen, T F, Frawley
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Effect of Sulfonylurea Compounds in Diabetic Children
New England Journal of Medicine, 1957IT has been the experience of those who have used the sulfonylurea compounds that they are, for the most part, not effective in children with diabetes or in adults with unstable, juvenile type of diabetes. Our findings with Carbutamide** and Tolbutamide†† have been in agreement with this, and in only 19 cases have we attempted to treat such patients ...
R, Camerini-Davalos +4 more
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Effects of Sulfonylurea Compounds on Pneumocystis carinii
Journal of Infectious Diseases, 1986Two sulfonylurea compounds, carbutamide and tolbutamide, were studied for efficacy against Pneumocystis carinii pneumonitis in the corticosteroid-treated rat model and compared with trimethoprim-sulfamethoxazole (TMP-SMZ). The chemical structures of these sulfonylureas are identical except that an amino group in carbutamide is replaced with a methyl ...
W T, Hughes, B L, Smith-McCain
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Divergent cardiac effects of the first and second generation hypoglycemic sulfonylurea compounds
Diabetes Research and Clinical Practice, 1990The effects of first and second generation hypoglycemic sulfonylureas on the incidence of ventricular ectopic beats and on the duration of transitional ventricular fibrillation in the ischemic rat heart were investigated. First generation sulfonylurea compounds (tolbutamide, carbutamide and gliclazide) in 105 preparations increased, while second ...
G, Ballagi-Pordány +4 more
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Acetohexamide: Comparison with other sulfonylurea compounds in the treatment of diabetes mellitus
Clinical Pharmacology & Therapeutics, 1962A new oral hypoglycemic agent, acetohexamide, is compared with four other sulfonylurea drugs in 70 patients with diabetes mellitus, the majority of whom had had either primary or secondary failure with other oral hypoglycemic compounds.Of the 70 patients studied, 43 per cent responded to acetohexamide, maintaining fasting blood sugar levels under 160 ...
B R, BOSHELL +3 more
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Comparative molecular field analysis (CoMFA) of new herbicidal sulfonylurea compounds
Science in China Series B: Chemistry, 1998A series of new herbicidal sulfonylurea compounds were investigated aiming at developing a three-dimensional quantitative structure-activity relationship (3D-QSAR) model using the CoMFA technique. On this base, some molecular structures were modified to improve their activities.
Jie Liu +6 more
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Protein Interactions of Sulfonylurea Compounds
JAMA: The Journal of the American Medical Association, 1963H. Wishinsky, E. Glasser, S. Perkal
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