Results 51 to 60 of about 272,763 (163)

The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function

Antioxidants, 2018
Cysteine and methionine residues are the amino acids most sensitive to oxidation by reactive oxygen species. However, in contrast to other amino acids, certain cysteine and methionine oxidation products can be reduced within proteins by dedicated ...
Sofia Lourenço dos Santos, Isabelle Petropoulos, Bertrand Friguet   +2 more
doaj   +1 more source

From perfluoroalkyl aryl sulfoxides to ortho thioethers

Beilstein Journal of Organic Chemistry
Access to original ortho thioether derivatives was achieved through a [3,3]-rearrangement in a one-pot two-step protocol. Several aryl-SCF3 compounds are reported by variation of the nitrile or of the trifluoroalkyl sulfoxide starting material.
Yang Li, Guillaume Dagousset, Emmanuel Magnier, Bruce Pégot   +3 more
doaj   +1 more source

The Structural Basis of the Activity Cliff in Modafinil-Based Dopamine Transporter Inhibitors

Biomolecules
Modafinil analogs with either a sulfoxide or sulfide moiety have improved binding affinities at the human dopamine transporter (hDAT) compared to modafinil, with lead sulfoxide-substituted analogs showing characteristics of atypical inhibition (e.g ...
Kuo-Hao Lee, Gisela Andrea Camacho-Hernandez, Amy Hauck Newman, Lei Shi   +3 more
doaj   +1 more source

Methionine oxidation products as biomarkers of oxidative damage to proteins and modulators of cellular metabolism and toxicity

Redox Biochemistry and Chemistry
Proteins are highly abundant and readily oxidized targets of reactive species formed in biological systems, with these often accounting for greater than 50 % of the dry mass of biological samples.
Michael J. Davies
doaj   +1 more source

Post-thaw dimethyl sulfoxide reduction in autologous peripheral blood progenitor cell suspensions

Hematology, Transfusion and Cell Therapy
Background and objectives: Dimethyl sulfoxide has become the most common cryoprotectant used for cryopreservation of hematopoietic progenitor cells because of its efficiency, regardless of its potentially toxic side effects. Its application is considered
Miroslava Jandová, Pavel Měřička, Jiří Gregor, Miriam Lánská, Aleš Bezrouk, Dana Čížková, Jakub Radocha   +6 more
doaj   +1 more source

Stereochemical Aspects of Sulfoxides and Metal Sulfoxide Complexes

Croatica Chemica Acta, 1999
Structural parameters of free and metal coordinated sulfoxides are reviewed and updated average values are derived. For uncoordinated sulfoxides, the average S−O bond distance is 1.4918(9) Å. This value is lengthened to 1.528(1) Å upon O-coordination to metal ions, while it is reduced to 1.4731(6) Å upon S-coordination.
openaire   +2 more sources

Single-atom substitution redirects KatG reactivity from cofactor biogenesis to stereoselective sulfoxidation. [PDF]

Nat Commun
Duan R, Li J, Griffith WP, Xu Y, Burrows ND, Green AP, Liu A.   +6 more
europepmc   +1 more source

Glycerolphosphorylethanolamine and Several Other Biochemical Amines Are Targets of Furan's Reactive Metabolite in Rodents. [PDF]

Chem Res Toxicol
Vevang KR, Trinh A, Raj M, Ocasio-Ramirez C, Zhao Y, von Weymarn LB, Peterson LA.   +6 more
europepmc   +1 more source

Deoxygenative Olefin Insertion of Cyclic Alcohols Promoted by Sulfoxide Cation Radicals. [PDF]

J Am Chem Soc
Genova JC, Cheng K, Nicewicz DA.
europepmc   +1 more source

BIOTIN SULFOXIDE

Journal of Biological Chemistry, 1954
openaire   +2 more sources