Results 141 to 150 of about 68,774 (280)

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

open access: yesJournal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel   +2 more
wiley   +1 more source

A GC-IRMS method for measuring sulfur isotope ratios of carbonyl sulfide from small air samples. [PDF]

open access: yesOpen Res Eur, 2021
Baartman SL   +6 more
europepmc   +1 more source

Metal sources for the Katanga Copperbelt deposits (DRC) insights from Sr and Nd isotope ratios [PDF]

open access: yes, 2014
The ore deposits of the Central African Copperbelt formed during a multiphase mineralisation process. The basement underlying the Neoproterozoic Katanga Supergroup that hosts the ore, demonstrates the largest potential as metal source.
El Desouky, Hamdy A   +4 more
core   +1 more source

Effect of ammonium concentration on methane oxidation and CO2 removal in an anaerobic biotrickling filter treating synthetic landfill gas and leachate

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Landfill gas (LFG) and leachate are commonly treated separately through energy‐intensive processes. This study evaluated the integration of both streams in an anaerobic biotrickling filter (BTF) to achieve simultaneous methane (CH4) and carbon dioxide (CO2) removal coupled with ammonium (NH4+) transformation, and how the microbial ...
Cecilia Lizeth Alvarez‐Guzmán   +3 more
wiley   +1 more source

Liebig Review: Essential and Beneficial Elements in the Regulation of Cadmium Uptake and Tolerance in Crop Plants

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Cadmium (Cd2+) contamination in agricultural soils has been reported to pose risks to crop productivity, food safety, and human health. This review synthesizes current knowledge on the mechanisms by which essential (S, Zn, Fe, Mg, K, Ca) and beneficial (Si, Se, rare earth elements) elements mitigate Cd2+ toxicity in plants.
Maria Manzoor, Karl Hermann Mühling
wiley   +1 more source

Deglaciation of the Burren glacio‐karst, western Ireland, during Termination 1: Implications for North Atlantic climate and karstification

open access: yesJournal of Quaternary Science, EarlyView.
Abstract The Burren uplands in western Ireland form one of the most extensive and best‐preserved examples of glacio‐karst in Europe. Subsumed by the Irish ice sheet during the Late Pleistocene, granite erratic boulders and in situ silica veins in the limestone bedrock provide a rare opportunity to reconstruct the timing and rate of deglaciation ...
Gordon Bromley   +4 more
wiley   +1 more source

Planetary biology and microbial ecology. Biochemistry of carbon and early life [PDF]

open access: yes
Experiments made with cyanobacteria, phototrophic bacteria, and methanogenic bacteria are detailed. Significant carbon isotope fractionation data is included.
Margulis, L., Nealson, K. H., Taylor, I.
core   +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt   +4 more
wiley   +1 more source

Ion Activation Methods for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Microbially driven organic carbon cycling at the land−sea interface: Advances and an integrated study framework

open access: yesmLife, EarlyView.
Abstract The land−sea interface is a vital component of global biogeochemical cycles, where microorganisms drive the cycling of carbon, nitrogen, and sulfur. This review synthesizes the research progress from representative land−sea interfaces to elucidate how the microbial community structure and metabolic function influence the mobilization ...
Quanrui Chen   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy