Results 71 to 80 of about 2,387 (211)

The effects of different garlic-derived allyl sulfides on anaerobic sulfur metabolism in the mouse kidney [PDF]

, 2016
Diallyl sulfide (DAS), diallyl disulfide (DADS) and diallyl trisulfide (DATS) are major oil-soluble organosulfur compounds of garlic responsible for most of its pharmacological effects.
Bilska-Wilkosz, Anna, Górny, Magdalena, Iciek, Małgorzata, Kowalczyk-Pachel, Danuta, Sokołowska-Jeżewicz, Maria   +4 more
core   +2 more sources

Hydrogen Sulfide Alleviates Schizophrenia‐Like Behavior Through Regulating Apoptosis by S‐Sulfhydrylation Modification

CNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
We explored the regulatory impacts and mechanisms of H2S on SZ at multiple levels in human, cellular, and animal models. Our findings indicated that H2S levels were significantly decreased in SZ patients and SZ model rats. Exogenous H2S supplementation might alleviate schizophrenia‐like behaviors by inhibiting apoptosis through S‐sulfhydrylation ...
Xinzhe Du, Wei Hu, Meiqi Liu, Jinzhi Lv, Yao Gao, Xiao Wang, Wentao Zhao, Junxia Li, Xinrong Li, Xiaohua Cao, Zhifen Liu, Yong Xu, Sha Liu   +12 more
wiley   +1 more source

Impaired Iron–Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy

Advanced Science, Volume 12, Issue 1, January 9, 2025.
A reduction in mitochondrial iron‐sulfur (Fe–S) cluster synthesis in diabetic cardiomyocytes decreases mitochondrial respiratory chain function, leading to oxidative stress and DNA damage. Supplementing with hydrogen sulfide (H2S) enhances Fe–S cluster synthesis via S‐sulfhydration of cysteine desulfurase (NFS1) at C383, preserving mitochondrial and ...
Mengyi Wang, Shiwu Zhang, Jinwei Tian, Fan Yang, He Chen, Shuzhi Bai, Jiaxin Kang, Kemiao Pang, Jiayi Huang, Mingjie Dong, Shiyun Dong, Zhen Tian, Shaohong Fang, Huitao Fan, Fanghao Lu, Bo Yu, Shuijie Li, Weihua Zhang   +17 more
wiley   +1 more source

Past, present and future of cyanide antagonism research: From the early remedies to the current therapies. [PDF]

, 2015
This paper reviews milestones in antidotal therapies for cyanide (CN) spanning early remedies, current antidotal systems and research towards next generation therapies. CN has been a part of plant defense mechanisms for millions of years.
Budai, Marianna, Kovacs K,, Petrikovics I,, Thompson DE,   +3 more
core   +2 more sources

Novel insights into the diversity of the sulfurtransferase family in photosynthetic organisms with emphasis on oak.

New Phytologist, 2020
Sulfurtransferases (STRs) constitute a large and complex protein family characterized by the presence of a rhodanese domain and implicated in diverse molecular and signaling processes as sulfur carriers.
Anna Moseler, Benjamin Selles, N. Rouhier, Jérémy Couturier   +3 more
semanticscholar   +1 more source

Impact of thermal processing on polyphenols, carotenoids, glucosinolates, and ascorbic acid in fruit and vegetables and their cardiovascular benefits

Comprehensive Reviews in Food Science and Food Safety, Volume 23, Issue 6, November 2024.
Abstract Bioactive compounds in fruit and vegetables have a positive impact on human health by reducing oxidative stress, inflammation, and the risk of chronic diseases such as cancer, cardiovascular (CV) diseases, and metabolic disorders. However, some fruit and vegetables must be heated before consumption and thermal processes can modify the amount ...
Federica Narra, Eugenia Piragine, Giada Benedetti, Costanza Ceccanti, Marta Florio, Jacopo Spezzini, Fabiola Troisi, Roberto Giovannoni, Alma Martelli, Lucia Guidi   +9 more
wiley   +1 more source

Hydrogen sulfide inhibits skeletal muscle ageing by up‐regulating autophagy through promoting deubiquitination of adenosine 5’‐monophosphate (AMP)‐activated protein kinase α1 via ubiquitin specific peptidase 5

Journal of Cachexia, Sarcopenia and Muscle, Volume 15, Issue 5, Page 2118-2133, October 2024.
Abstract Background Hydrogen sulfide (H2S), the third gasotransmitter discovered, regulates a variety of physiological functions. Whether H2S alleviates skeletal muscle ageing by regulating autophagy has not been reported. Methods Mice were administered 150 mg/kg/day of D‐galactose (D‐gal), and C2C12 myotubes were cultured in 20 g/L D‐gal to induce ...
Jia‐He Yang, Jun Gao, Ya‐Qi E, Li‐Jie Jiao, Ren Wu, Qiu‐Yi Yan, Zi‐Yi Wei, Guo‐Liang Yan, Jin‐Long Liang, Hong‐Zhu Li   +9 more
wiley   +1 more source

Metagenomic Analysis Reveals Large‐Scale Disruptions of the Gut Microbiome in Parkinson's Disease

Movement Disorders, Volume 39, Issue 10, Page 1740-1751, October 2024.
Abstract Background Parkinson's disease (PD) has been consistently linked to alterations within the gut microbiome. Objective Our goal was to identify microbial features associated with PD incidence and progression. Methods Metagenomic sequencing was used to characterize taxonomic and functional changes to the PD microbiome and to explore their ...
Avril Metcalfe‐Roach, Mihai S. Cirstea, Adam C. Yu, Hena R. Ramay, Olabisi Coker, Seti Boroomand, Faezeh Kharazyan, Davide Martino, Laura K. Sycuro, Silke Appel‐Cresswell, B. Brett Finlay   +10 more
wiley   +1 more source

Role of hydrogen sulfide in health and disease

MedComm, Volume 5, Issue 9, September 2024.
Abstract In the past, hydrogen sulfide (H2S) was recognized as a toxic and dangerous gas; in recent years, with increased research, we have discovered that H2S can act as an endogenous regulatory transmitter. In mammals, H2S‐catalyzing enzymes, such as cystathionine‐β‐synthase, cystathionine‐γ‐lyase, and 3‐mercaptopyruvate sulfurtransferase, are ...
Yu‐Qing Jin, Hang Yuan, Ya‐Fang Liu, Yi‐Wen Zhu, Yan Wang, Xiao‐Yi Liang, Wei Gao, Zhi‐Guang Ren, Xin‐Ying Ji, Dong‐Dong Wu   +9 more
wiley   +1 more source

Interaction between Sox proteins of two physiologically distinct bacteria and a new protein involved in thiosulfate oxidation [PDF]

, 2009
Organisms using the thiosulfate-oxidizing Sox enzyme system fall into two groups: group 1 forms sulfur globules as intermediates (Allochromatium vinosum), group 2 does not (Paracoccus pantotrophus). While several components of their Sox systems are quite
Dahl, Christiane, Friedrich, Cornelius G., Hafner, Swetlana, Krätzer, Christian, Quentmeier, Armin, Welte, Cornelia   +5 more
core   +1 more source