Results 71 to 80 of about 2,505 (224)

Hydrogen Sulfide Protects Erectile Function Through Stimulation of Antioxidant Defense in the Corpus Cavernosum: Insights From SG1002 Administration and Cystathionine γ‐Lyase Knockout

The FASEB Journal, Volume 39, Issue 15, 15 August 2025.
Chronic consumption of a western diet suppressed corpus cavernosum cystathionine γ‐lyase (CSE) protein content and H2S production and was associated with elevated penile reactive oxygen species (ROS) levels and impaired erectile function. CSE knockout mice demonstrate impaired erectile function, elevated penile ROS levels, and suppressed corpus ...
Tooyib A. Azeez, Paige R. Rhein, Clifford J. Pierre, Colin M. Ihrig, Justin D. La Favor   +4 more
wiley   +1 more source

Investigating the Catalytic and the Metabolic Role of the Thiol Dioxygenase and a Sulfurtransferase in the mdo Operon from Pseudomonas aeruginosa [PDF]

, 2019
Mammalian cysteine dioxygenase (CDO) is a mononuclear iron containing enzyme that belongs to the cupin superfamily. CDO catalyzes the oxidation of cysteine to cysteine sulfinic acid.
Laura, Tombrello
core  

Development and Application of a 1,8‐Naphthalimide‐Based Fluorescent Probe for Sensitive Detection of Hydrogen Sulfide in Human Blood Serum

Luminescence, Volume 40, Issue 8, August 2025.
The target 1,8‐napthalimide‐based fluorescent probe was prepared and successfully applied for H2S detection in human blood serum whereby the concentration of H2S in human blood serum was found to be 16.2 μmol L−1. The accuracy of the developed method was confirmed by the standard addition method and UV‐Vis spectrophotometry method using methylene blue.
Aleksandar Széchenyi, Mirela Samardžić, Mateja Budetić, Ines Drenjančević, Nikolina Kolobarić, Gábor Mikle, Barna Kovács, Andrea Dandić   +7 more
wiley   +1 more source

Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically-relevant concentrations [PDF]

, 2020
Pramod Kumar Yadav, Victor Vitvitsky, Sebastián Carballal, Javier Seravalli, Ruma Banerjee   +4 more
openalex   +1 more source

MTA‐TST Axis‐Mediated Apoptosis Activation: A Multi‐Omics Insight Into High‐Protein Diet's Anti‐Adiposity Effect

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
High protein diet reduced visceral adipose tissue through MTA‐TST‐Bak/Casp‐3 axis, suggesting that MTA has the potential to be developed as a functional substance for obesity prevention and control. ABSTRACT To explore the mechanism of a high‐protein diet (named high protein and rich fat diet, HPRFD) with weight loss effect regulating visceral fat ...
Xinli Yang, Yueyue Wang, Zhe Shi, Aiting Wang, Jianglan Long, Dan Yan   +5 more
wiley   +1 more source

Cystathionine gamma‐lyase‐mediated hypoxia inducible factor 1‐alpha expression drives clear cell ovarian cancer progression

The Journal of Pathology, Volume 266, Issue 3, Page 352-367, July 2025.
Abstract Clear cell ovarian cancer (CCOC) is the second most common ovarian cancer subtype, accounting for 5%–11% of ovarian cancers in North America. Late‐stage CCOC is associated with a worse prognosis compared to other ovarian cancer histotypes, a challenge that has seen limited progress in recent decades.
Amal M EL‐Naggar, Yuqin Li, Busra Turgu, Yuchen Ding, Longyijie Wei, Shary Yuting Chen, Genny Trigo‐Gonzalez, Forouh Kalantari, Rodrigo Vallejos, Branden Lynch, Janine Senz, Amy Lum, J Maxwell Douglas, Clara Salamanca, Shelby Thornton, Yimei Qin, Kiran Parmar, Sandra E Spencer, Samuel Leung, Michelle M M Woo, Paul J Yong, Hai‐Feng Zhang, Christopher S Hughes, Gian Luca Negri, Yemin Wang, Gregg B Morin, Poul H Sorensen, David G Huntsman   +27 more
wiley   +1 more source

Alternative sulfur acquisition pathways in Neisseria gonorrhoeae [PDF]

, 2021
Neisseria gonorrhoeae is an obligate human pathogen responsible for the sexually transmitted infection, gonorrhoea. Its success as a pathogen is partly due to robust defence mechanisms that provide protection against oxidative stress encountered during ...
van Niekerk, Stacy Lyn
core  

Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase

Biochemical Pharmacology, 2020
Hydrogen sulfide (H2S) is a physiological mediator that regulates cardiovascular homeostasis. Three major enzymes contribute to the generation of endogenously produced H2S, namely cystathionine γ-lyase (CSE), cystathionine β-synthase (CBS) and 3-mercaptopyruvate sulfurtransferase (3-MST).
Maria Peleli, Sofia-Iris Bibli, Zhen Li, Athanasia Chatzianastasiou, Aimilia Varela, Antonia Katsouda, Sven Zukunft, Mariarosaria Bucci, Valentina Vellecco, Constantinos H Davos, Noriyuki Nagahara, Giuseppe Cirino, Ingrid Fleming, David J Lefer, Andreas Papapetropoulos   +14 more
openaire   +4 more sources

S‐Propargyl‐Cysteine Attenuates Stroke Heterogeneity via Promoting Protective Autophagy Across Multiple Neural Cell Types: Insights From Single‐Cell Sequencing

CNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.
Stroke is one of the major contributors to mortality and long‐term disability. Treatments aiming at regulating endogenous protective mechanisms to reduce neurological injury after ischemic stroke are still urgently needed. Herein, we investigated the neuroprotective potential of S‐propargyl‐cysteine (SPRC), a novel water‐soluble donor of H2S, and its ...
Xiaoming Xin, Lei Miao, Lei Ci, Yun Wang, Zhiguo Zhang, Lingguo Meng, Jia Qi, Yicheng Mao, Yi‐Zhun Zhu   +8 more
wiley   +1 more source

Identification of protein partners of the Azotobacter vinelandii rhodanese-like protein RhdA by pull-down approaches [PDF]

Rhodaneses (TST; EC 2.8.1.1) catalyze in vitro the transfer of sulfane sulfur from thiosulfate to cyanide with the concomitant formation of thiocyanate.
Forlani, Fabio, Guerrieri, Nicoletta, Remelli, William, Seregni, Morena   +3 more
core