Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning
The FASEB Journal, Volume 39, Issue 12, 30 June 2025.Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley +1 more source
The glial Gomori-positive material is sulfane sulpfur. [PDF]
, 2008 The Gomori-positive glia are periventricular astrocytes with abundant cytoplasmic granular material, predominantly occupying a periventricular site in the brain.
Góralska, Marta +3 more
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Analytical Chemistry, 2019 Glutathione hydropersulfides (GSSH) are alluded to play crucial roles in signal transduction, redox homeostasis, and metabolic regulation. However, the detailed biological functions of GSSH in these aspects are extremely ambiguous.
Yue Wang +4 more
semanticscholar +1 more source
Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty [PDF]
, 1971 Recent experimental information on DNA sequence repetition is reviewed, and the significance of both repetitive and non-repetitive sequence considered.
Britten, Roy J., Davidson, Eric H.
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The effects of different garlic-derived allyl sulfides on anaerobic sulfur metabolism in the mouse kidney [PDF]
, 2016 Diallyl sulfide (DAS), diallyl disulfide (DADS) and diallyl trisulfide (DATS) are major oil-soluble organosulfur compounds of garlic responsible for most of its pharmacological effects.
Bilska-Wilkosz, Anna +4 more
core +2 more sources
Acute health risks related to the presence of cyanogenic glycosides in raw apricot kernels and products derived from raw apricot kernels [PDF]
, 2018 Peer reviewedPublisher ...
Alexander, Jan +21 more
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Thiosulfate sulfurtransferase and UDP-glucuronosyltransferase activities in cholestatic rat liver induced by common bile duct ligation [PDF]
, 1997 Jong-Sool Ihm, You-Hee Kim
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Structure of an E. coli integral membrane sulfurtransferase and its structural transition upon SCN− binding defined by EPR-based hybrid method [PDF]
, 2016 Shenglong Ling +10 more
openalex +1 more source
Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway [PDF]
, 2017 Meng Li +13 more
openalex +1 more source
Protein persulfidation in plants : Mechanisms and functions beyond a simple stress response [PDF]
Posttranslational modifications (PTMs) can modulate the activity, localization and interactions of proteins and (re)define their biological function. Understanding how changing environments can alter cellular processes thus requires detailed knowledge ...
Meyer, Andreas J. +2 more
core +1 more source