Results 261 to 270 of about 41,584 (297)

3D‐Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
3D‐printed organoid scaffolds with microscale channels are developed to enhance spinal cord injury recovery by guiding region‐specific spinal neural progenitor cells. These scaffolds promote axonal growth, cell maturation, and neuronal network formation.
Guebum Han   +8 more
wiley   +1 more source

An Update on Mitral Valve Aging. [PDF]

open access: yesLife (Basel)
Opris CE, Suciu H, Opris CI, Gurzu S.
europepmc   +1 more source

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

open access: yesAdvanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo   +8 more
wiley   +1 more source

The VEGF decoy receptor soluble Fms-like tyrosine kinase 1 binds to macrophages. [PDF]

open access: yesAngiogenesis
van Aanhold CCL   +13 more
europepmc   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

open access: yesAdvanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun   +13 more
wiley   +1 more source

Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins

open access: yesAdvanced Healthcare Materials, EarlyView.
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer   +8 more
wiley   +1 more source

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng   +6 more
wiley   +1 more source

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