Results 51 to 60 of about 217,223 (279)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
On Maximum Signless Laplacian Estrada Indices of Graphs with Given Parameters [PDF]
, 2014 Signless Laplacian Estrada index of a graph $G$, defined as $SLEE(G)=\sum^{n}_{i=1}e^{q_i}$, where $q_1, q_2, \cdots, q_n$ are the eigenvalues of the matrix $\mathbf{Q}(G)=\mathbf{D}(G)+\mathbf{A}(G)$. We determine the unique graphs with maximum signless
Ellahi, H. R. +3 more
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Topological Indices of Families of Bistar and Corona Product of Graphs
Journal of Mathematics, 2022 Topological indices are graph invariants that are used to correlate the physicochemical properties of a chemical compound with its (molecular) graph. In this study, we study certain degree-based topological indices such as Randić index, Zagreb indices ...
A. Khalid +5 more
doaj +1 more source
Correlated connectivity and the distribution of firing rates in the neocortex [PDF]
, 2008 Two recent experimental observations pose a challenge to many cortical models. First, the activity in the auditory cortex is sparse, and firing rates can be described by a lognormal distribution.
Hromadka, Tomas +2 more
core +2 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Exact results for fixation probability of bithermal evolutionary graphs
, 2012 One of the most fundamental concepts of evolutionary dynamics is the "fixation" probability, i.e. the probability that a mutant spreads through the whole population.
Houchmandzadeh, Bahram, Vallade, Marcel
core +3 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
AKCE International Journal of Graphs and Combinatorics, 2017 The general sum-connectivity index, general product-connectivity index, general Zagreb index and coindices of line graphs of subdivision graphs of tadpole graphs, wheels and ladders have been reported in the literature.
Harishchandra S. Ramane +2 more
doaj +1 more source
Investigation of General Power Sum-Connectivity Index for Some Classes of Extremal Graphs
Complexity, 2021 In this work, we introduce a new topological index called a general power sum-connectivity index and we discuss this graph invariant for some classes of extremal graphs.
Rui Cheng +5 more
doaj +1 more source