Results 81 to 90 of about 1,800,802 (268)

SUM Technical Requirements Document

open access: yes, 2009
This document describes the technical requirements of the Surveillance in an Urban environment using Mobile sensors (SUM) Project as requested in annex A of the SUM project proposal: Proposal database template, document EDA A0444RTGC JIP-FP, section A4 ...
Rudolf, Daniel   +3 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Complication management in percutaneous dilatational tracheostomy: a case of tracheal needle sheath retrieval

open access: yesInternational Journal of Emergency Medicine
Background Percutaneous dilatational tracheostomy (PDT) is a widely performed procedure in intensive care units (ICUs) for patients requiring prolonged mechanical ventilation. Although generally safe, PDT carries risks of complications, some of which may
Sritam Mohanty   +5 more
doaj   +1 more source

Understanding User Behaviour in Autonomous Mobility: A Literature Review on Value of Time, Willingness to Pay, and Onboard Services

open access: yesFuture Transportation
Autonomous mobility is reshaping how travel time is perceived, experienced, and monetised. Most existing studies have examined the value of time (VOT), willingness to pay (WTP), comfort and safety perception, digital services, and user perception as ...
Issa Mahamied   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Nonzero-sum Stochastic Games

open access: yes
This paper treats of stochastic games. We focus on nonzero-sum games and provide a detailed survey of selected recent results. In Section 1, we consider stochastic Markov games. A correlation of strategies of the players, involving ``public signals'', is
Szajowski, Krzysztof, Nowak, Andrzej S.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Radiological findings in fulminant cerebral malaria: a rare neuroimaging presentation

open access: yesMalaria Journal
Background Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum infection, characterized by coma, seizures, and multiorgan dysfunction.
Biswajit Nayak   +4 more
doaj   +1 more source

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