Results 141 to 150 of about 168,667 (308)
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
ON THE MAXIMUM PARTIAL SUM OF INDEPENDENT RANDOM VARIABLES [PDF]
Proceedings of the National Academy of Sciences, 1947 openaire +2 more sources
On the Central Limit Theorem of Random Sum of Independent Random Variables Using Stein’s Method [PDF]
Stein’s method provides a powerful tool for quantifying the distance between a random variable and a normal distribution without relying on the characteristic function as in the traditional method.
Huang, Yichen
core
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Bezpieczeństwo Liny jako Złożonego Elementu Konstrukcyjnego
Engineering Transactions, 1965 In composite structural elements subject to tension, such as ropes, cables, sets of wires or bars in r.c. structures etc. the number n of component elements has an essential influence on the safety of the structure.
W. Piekarski
doaj
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
On the product and the sum of random variables with arithmetic and non-arithmetic distributions
We show that the distribution of the product and the sum of independent random variables having arithmetic distributions is again arithmetic. In case of the product, it is also possible to give a formula for the span.
Abt, Markus
core
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
On the evaluation of 'saving-consumption' plans. [PDF]
Knowledge of the distribution function of the stochastically compounded value of a series of future (positive and/or negative) payments is needed for solving several problems in an insurance or finance environment, see e.g. Dhaene et al. (2002 a,b).
Goovaerts, Marc +2 more
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