Results 101 to 110 of about 898,395 (346)

Estimating Reliability for Frechet (3+1) Cascade Model

open access: yesJambura Journal of Mathematics
In this paper, the mathematical formula of the reliability function of a special (3+1) cascade model is found, where this model can work with three active components if it is able to cope with the stresses to which it is subjected, while the cascade 3+1 ...
Ahmed Haroon Khaleel
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Quiet Sun Explosive Events: Jets, Splashes, and Eruptions

open access: yes, 2012
Explosive events are small transition region phenomena characterised by broad non-Gaussian wings in their line profiles. Images from the Solar Dynamics Observatory (SDO) give a first view of the plasma dynamics at the sites of explosive events seen in O ...
Innes, Davina, Teriaca, Luca
core   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Tummali ajalugu. Mõningaid märkusi muistsete Sumeri kuningate ja nende kuningavõimu ideoloogia kohta [PDF]

open access: yesMäetagused, 2013
The current short but very important Sumerian literary text, which was written in the Sumerian language at the end of the reign of Ur III (2112–2004 BCE) or at the beginning of the Isin-Larsa epoch (ca 21st or 20th century BCE), consists of only 33 lines.
Vladimir Sazonov
doaj  

Standing Slow-Mode Waves in Hot Coronal Loops: Observations, Modeling, and Coronal Seismology

open access: yes, 2010
Strongly damped Doppler shift oscillations are observed frequently associated with flarelike events in hot coronal loops. In this paper, a review of the observed properties and the theoretical modeling is presented.
Wang, Tongjiang
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

SUMER: Solar Ultraviolet Measurements of Emitted Radiation [PDF]

open access: yes
The SUMER (solar ultraviolet measurements of emitted radiation) experiment is described. It will study flows, turbulent motions, waves, temperatures and densities of the plasma in the upper atmosphere of the Sun.
Axford, W. I.   +9 more
core   +1 more source

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