Results 81 to 90 of about 11,227 (296)
Estimating Reliability for Frechet (3+1) Cascade Model
Jambura Journal of MathematicsIn this paper, the mathematical formula of the reliability function of a special (3+1) cascade model is found, where this model can work with three active components if it is able to cope with the stresses to which it is subjected, while the cascade 3+1 ...
Ahmed Haroon Khaleel
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
, 1996 Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1996.Includes bibliographical references (p. 140).by Sumer S.
Johal, Sumer S. (Sumer Singh)
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Hartmut Schmökel. — Das Land Sumer.
, 1955 Parrot André. Hartmut Schmökel. — Das Land Sumer.. In: Syria. Tome 32 fascicule 3-4, 1955. pp.
Parrot, André
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Correction: Effects of droplet size and surfactants on anchoring in liquid crystal nanodroplets [PDF]
, 2020 Correction for ‘Effects of droplet size and surfactants on anchoring in liquid crystal nanodroplets’ by Zeynep Sumer et al., Soft Matter, 2019, 15, 3914–3922, DOI: 10.1039 ...
Sumer, Z, Striolo, A
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source